The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

SCAR  -  CG4636 gene product from transcript CG4636-RD

Drosophila melanogaster

Synonyms: BEST:SD02991, CG4636, D-SCAR, DWave, DmSCAR, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

Disease relevance of SCAR

 

High impact information on SCAR

  • Late in larval development, as differentiation and patterning begin, the retinal epithelium exhibits striking regulation of the cell cycle including a transient G1 arrest of all cells, followed by a "Second Mitotic Wave" cell cycle that is regulated at the G2/M transition by local intercellular signals [2].
  • Finally, RNA interference studies in S2 cells indicated that the D-SCAR homolog D-WASp also participates in phagocytosis [1].
  • Analysis of double mutants suggests that D-SCAR and profilin interact during phagocytosis [1].

References

  1. Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila. Pearson, A.M., Baksa, K., Rämet, M., Protas, M., McKee, M., Brown, D., Ezekowitz, R.A. Microbes Infect. (2003) [Pubmed]
  2. Cell proliferation, survival, and death in the Drosophila eye. Baker, N.E. Semin. Cell Dev. Biol. (2001) [Pubmed]
 
WikiGenes - Universities