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Gene Review

Or43a  -  Odorant receptor 43a

Drosophila melanogaster

Synonyms: 43B.1, 43B1, 43a, AN14, CG1854, ...
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High impact information on Or43a


Biological context of Or43a

  • In order to gain insight into the principles of olfactory processing in Drosophila, we misexpressed olfactory receptor Or43a in additional olfactory receptor neurons of the third antennal segment using enhancer trap line GH320 [6].
  • The convergence of olfactory axons expressing particular odorant receptor (Or) genes on spatially invariant glomeruli in the brain is one of the most dramatic examples of precise axon targeting in developmental neurobiology [7].

Associations of Or43a with chemical compounds


  1. The molecular basis of odor coding in the Drosophila larva. Kreher, S.A., Kwon, J.Y., Carlson, J.R. Neuron (2005) [Pubmed]
  2. Integrating the molecular and cellular basis of odor coding in the Drosophila antenna. Dobritsa, A.A., van der Goes van Naters, W., Warr, C.G., Steinbrecht, R.A., Carlson, J.R. Neuron (2003) [Pubmed]
  3. Molecular evolution of the insect chemoreceptor gene superfamily in Drosophila melanogaster. Robertson, H.M., Warr, C.G., Carlson, J.R. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
  4. Functional analysis of an olfactory receptor in Drosophila melanogaster. Störtkuhl, K.F., Kettler, R. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  5. Functional expression and characterization of a Drosophila odorant receptor in a heterologous cell system. Wetzel, C.H., Behrendt, H.J., Gisselmann, G., Störtkuhl, K.F., Hovemann, B., Hatt, H. Proc. Natl. Acad. Sci. U.S.A. (2001) [Pubmed]
  6. An increased receptive field of olfactory receptor Or43a in the antennal lobe of Drosophila reduces benzaldehyde-driven avoidance behavior. Störtkuhl, K.F., Kettler, R., Fischer, S., Hovemann, B.T. Chem. Senses (2005) [Pubmed]
  7. Dock and Pak regulate olfactory axon pathfinding in Drosophila. Ang, L.H., Kim, J., Stepensky, V., Hing, H. Development (2003) [Pubmed]
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