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Gene Review

BANF1  -  barrier to autointegration factor 1

Bos taurus

 
 
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Disease relevance of BANF1

 

High impact information on BANF1

  • Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling [2].
  • PIP2, which is regulated by activation stimuli, is sufficient in vitro to target the BAF complex to chromatin, but it has no effect on related chromatin remodeling complexes containing SNF2L or hISWI [2].
  • BAF differentially modulate HA and CS synthesis of articular chondrocytes as a result of maturation and topography [1].
  • Adult chondrocytes from the deep zone had large responses to the BAF for HA but not CS synthesis, resembling the subpopulations of the calf chondrocytes [1].
 

Associations of BANF1 with chemical compounds

  • To determine if bone associated peptide factors (BAF) differentially affect proteoglycan and hyaluronic acid (HA) synthesis as a result of the maturity of the animal and of the location of chondrocytes within cartilage zones [1].

References

 
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