The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia

Table of contents

About

Terms

 

Gene Review: 

EloC  -  Elongin C

Drosophila melanogaster

Synonyms: BcDNA:RH71704, CG9291, Dmel\CG9291, Elongin-C, ElonginC, ...
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on Elongin-C

  • In this report, we show that the Elongin B ubiquitin-like domain is necessary and sufficient for interaction with Elongin C and for positive regulation of Elongin A transcriptional activity [1].
  • It showed an overall 50% similarity to the human counterpart and 76% similarity in the crucial functional domain: the elongin C binding site [2].
  • Moreover, yeast Elongin C strongly induces the transcriptional elongation activity of mammalian Elongin A [3].
 

Analytical, diagnostic and therapeutic context of Elongin-C

References

  1. The elongin B ubiquitin homology domain. Identification of Elongin B sequences important for interaction with Elongin C. Brower, C.S., Shilatifard, A., Mather, T., Kamura, T., Takagi, Y., Haque, D., Treharne, A., Foundling, S.I., Conaway, J.W., Conaway, R.C. J. Biol. Chem. (1999) [Pubmed]
  2. Tracheal development and the von Hippel-Lindau tumor suppressor homolog in Drosophila. Adryan, B., Decker, H.J., Papas, T.S., Hsu, T. Oncogene (2000) [Pubmed]
  3. Molecular cloning of DNAs encoding the regulatory subunits of elongin from Saccharomyces cerevisiae and Drosophila melanogaster. Aso, T., Conrad, M.N. Biochem. Biophys. Res. Commun. (1997) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities