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Gene Review

KCNJ14  -  potassium channel, inwardly rectifying...

Homo sapiens

Synonyms: ATP-sensitive inward rectifier potassium channel 14, IRK-4, IRK4, Inward rectifier K(+) channel Kir2.4, KIR2.4, ...
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Analytical, diagnostic and therapeutic context of KCNJ14

  • Low Ba2+ sensitivity allows dissection of Kir2.4 currents from other Kir conductances in hypoglossal motoneurons (HMs) in rat brainstem slices [1].


  1. Kir2.4: a novel K+ inward rectifier channel associated with motoneurons of cranial nerve nuclei. Töpert, C., Döring, F., Wischmeyer, E., Karschin, C., Brockhaus, J., Ballanyi, K., Derst, C., Karschin, A. J. Neurosci. (1998) [Pubmed]
  2. Direct activation of an inwardly rectifying potassium channel by arachidonic acid. Liu, Y., Liu, D., Heath, L., Meyers, D.M., Krafte, D.S., Wagoner, P.K., Silvia, C.P., Yu, W., Curran, M.E. Mol. Pharmacol. (2001) [Pubmed]
  3. Cloning and functional expression of human retinal kir2.4, a pH-sensitive inwardly rectifying K(+) channel. Hughes, B.A., Kumar, G., Yuan, Y., Swaminathan, A., Yan, D., Sharma, A., Plumley, L., Yang-Feng, T.L., Swaroop, A. Am. J. Physiol., Cell Physiol. (2000) [Pubmed]
  4. Cloning, structure and assignment to chromosome 19q13 of the human Kir2.4 inwardly rectifying potassium channel gene (KCNJ14). Töpert, C., Döring, F., Derst, C., Daut, J., Grzeschik, K.H., Karschin, A. Mamm. Genome (2000) [Pubmed]
  5. A refined radiation hybrid map of the telomeric region of bovine chromosome 18q25-q26 compared with human chromosome 19q13. Mömke, S., Kuiper, H., Spötter, A., Drögemüller, C., Distl, O. Anim. Genet. (2005) [Pubmed]
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