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Gene Review:

tfap2a - transcription factor AP-2 alpha...

Xenopus (Silurana) tropicalis

Synonyms: AP-2, AP2a, AP2alpha, XAP-2, ap-2alpha, ...

Luo, T. et al., French, R.P. et al., Winning, R.S. et al.

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High impact information on tfap2a

Developmental regulation of transcription factor AP-2 during Xenopus laevis embryogenesis [1].
The transcription factor AP-2 is expressed at high levels in the skin of premetamorphic larvae and induced about fivefold by T3 but is not induced in an epithelial cell line (XL-177) [2].
The transcription factor AP2 (TFAP2) has an important role in regulating gene expression in both epidermis and neural crest cells [3].

Anatomical context of tfap2a

A second group was expressed at high levels in the neural crest, but all of these were also expressed in the epidermis as well as in other tissues in which TFAP2alpha has not been detected, suggesting modular control involving both TFAP2-dependent and TFAP2-independent components [3].

References

Developmental regulation of transcription factor AP-2 during Xenopus laevis embryogenesis. Winning, R.S., Shea, L.J., Marcus, S.J., Sargent, T.D. Nucleic Acids Res. (1991) [Pubmed]
Upregulation of AP-2 in the skin of Xenopus laevis during thyroid hormone-induced metamorphosis. French, R.P., Warshawsky, D., Tybor, L., Mylniczenko, N.D., Miller, L. Dev. Genet. (1994) [Pubmed]
Regulatory targets for transcription factor AP2 in Xenopus embryos. Luo, T., Zhang, Y., Khadka, D., Rangarajan, J., Cho, K.W., Sargent, T.D. Dev. Growth Differ. (2005) [Pubmed]

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AgaP_AGAP011625	Anopheles gambiae str. PEST
TFAP2A	Bos taurus
LOC488213	Canis lupus familiaris
tfap2a	Danio rerio
TfAP-2	Drosophila melanogaster
TFAP2A	Gallus gallus
TFAP2A	Homo sapiens
TFAP2A	Macaca mulatta
Tfap2a	Mus musculus
TFAP2A	Pan troglodytes
Tfap2a	Rattus norvegicus

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