Gene Review:
Tfap2a - transcription factor AP-2, alpha
Mus musculus
Synonyms:
AP-2, AP-2 alpha, AP-2 transcription factor, AP2-alpha, AP2alpha, ...
- An ENU-induced mutation in AP-2alpha leads to middle ear and ocular defects in Doarad mice. Ahituv, N., Erven, A., Fuchs, H., Guy, K., Ashery-Padan, R., Williams, T., de Angelis, M.H., Avraham, K.B., Steel, K.P. Mamm. Genome (2004)
- Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Zhang, J., Hagopian-Donaldson, S., Serbedzija, G., Elsemore, J., Plehn-Dujowich, D., McMahon, A.P., Flavell, R.A., Williams, T. Nature (1996)
- In vivo interferon regulatory factor 3 tumor suppressor activity in B16 melanoma tumors. Duguay, D., Mercier, F., Stagg, J., Martineau, D., Bramson, J., Servant, M., Lin, R., Galipeau, J., Hiscott, J. Cancer Res. (2002)
- Cell type-specific and sexually dimorphic expression of transcription factor AP-2 in the adult mouse brain. Coelho, D.J., Sims, D.J., Ruegg, P.J., Minn, I., Muench, A.R., Mitchell, P.J. Neuroscience (2005)
- Transcription factor AP-2 essential for cranial closure and craniofacial development. Schorle, H., Meier, P., Buchert, M., Jaenisch, R., Mitchell, P.J. Nature (1996)
- Enhanced apoptotic cell death of renal epithelial cells in mice lacking transcription factor AP-2beta. Moser, M., Pscherer, A., Roth, C., Becker, J., Mücher, G., Zerres, K., Dixkens, C., Weis, J., Guay-Woodford, L., Buettner, R., Fässler, R. Genes Dev. (1997)
- Transcription factor AP-2 is expressed in neural crest cell lineages during mouse embryogenesis. Mitchell, P.J., Timmons, P.M., Hébert, J.M., Rigby, P.W., Tjian, R. Genes Dev. (1991)
- Cell type-specific regulation of expression of transcription factor AP-2 in neuroectodermal cells. Philipp, J., Mitchell, P.J., Malipiero, U., Fontana, A. Dev. Biol. (1994)
- Analysis of transcription factor AP-2 expression and function during mouse preimplantation development. Winger, Q., Huang, J., Auman, H.J., Lewandoski, M., Williams, T. Biol. Reprod. (2006)
- Effect of clathrin heavy chain- and alpha-adaptin-specific small inhibitory RNAs on endocytic accessory proteins and receptor trafficking in HeLa cells. Hinrichsen, L., Harborth, J., Andrees, L., Weber, K., Ungewickell, E.J. J. Biol. Chem. (2003)
- Decreased neural crest stem cell expansion is responsible for the conotruncal heart defects within the splotch (Sp(2H))/Pax3 mouse mutant. Conway, S.J., Bundy, J., Chen, J., Dickman, E., Rogers, R., Will, B.M. Cardiovasc. Res. (2000)
- Redundant activities of Tfap2a and Tfap2c are required for neural crest induction and development of other non-neural ectoderm derivatives in zebrafish embryos. Li, W., Cornell, R.A. Dev. Biol. (2007)
- Sox9 is required for determination of the chondrogenic cell lineage in the cranial neural crest. Mori-Akiyama, Y., Akiyama, H., Rowitch, D.H., de Crombrugghe, B. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Transcription factor activator protein-2 is required for continued luteinizing hormone-releasing hormone expression in the forebrain of developing mice. Kramer, P.R., Krishnamurthy, R., Mitchell, P.J., Wray, S. Endocrinology (2000)
- Cloning and characterization of a second AP-2 transcription factor: AP-2 beta. Moser, M., Imhof, A., Pscherer, A., Bauer, R., Amselgruber, W., Sinowatz, F., Hofstädter, F., Schüle, R., Buettner, R. Development (1995)
- AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle. West-Mays, J.A., Zhang, J., Nottoli, T., Hagopian-Donaldson, S., Libby, D., Strissel, K.J., Williams, T. Dev. Biol. (1999)
- Association of epidermal growth factor receptors with coated pit adaptins via a tyrosine phosphorylation-regulated mechanism. Nesterov, A., Kurten, R.C., Gill, G.N. J. Biol. Chem. (1995)
- Reduction of adrenal and kidney epinephrine and phenylethanolamine N-methyltransferase in AP-2 knockout mouse fetuses. Kennedy, B., Enns, R., Nelson, D., Williams, T., Bao, X., Ziegler, M.G. Ann. N. Y. Acad. Sci. (2002)
- Regulation of AP-2 and apoptosis in developing eye in a vitamin A-deficiency model. Zhou, J., Kochhar, D.M. Birth defects research. Part A, Clinical and molecular teratology. (2003)
- A proline-rich transcriptional activation domain in murine HOXD-4 (HOX-4.2). Rambaldi, I., Kovàcs, E.N., Featherstone, M.S. Nucleic Acids Res. (1994)
- AP2-dependent signals from the ectoderm regulate craniofacial development in the zebrafish embryo. Knight, R.D., Javidan, Y., Zhang, T., Nelson, S., Schilling, T.F. Development (2005)
- Transcription factor AP-2gamma regulates murine adenosine deaminase gene expression during placental development. Shi, D., Kellems, R.E. J. Biol. Chem. (1998)
- Comparative analysis of AP-2 alpha and AP-2 beta gene expression during murine embryogenesis. Moser, M., Rüschoff, J., Buettner, R. Dev. Dyn. (1997)
- Characterisation of the Mouse Vasoactive Intestinal Peptide Receptor Type 2 Gene, Vipr2, and Identification of a Polymorphic LINE-1-like Sequence That Confers Altered Promoter Activity. Steel, G., Lutz, E.M. J. Neuroendocrinol. (2007)
- Regulation of Hoxa2 in cranial neural crest cells involves members of the AP-2 family. Maconochie, M., Krishnamurthy, R., Nonchev, S., Meier, P., Manzanares, M., Mitchell, P.J., Krumlauf, R. Development (1999)
- Molecular cloning and characterization of AP-2 epsilon, a fifth member of the AP-2 family. Tummala, R., Romano, R.A., Fuchs, E., Sinha, S. Gene (2003)
- Association and colocalization of Eps15 with adaptor protein-2 and clathrin. van Delft, S., Schumacher, C., Hage, W., Verkleij, A.J., van Bergen en Henegouwen, P.M. J. Cell Biol. (1997)