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Gene Review:

NRXN1 - neurexin 1

Gallus gallus

Paraoanu, L.E. et al., Ernsberger, U. et al.

Paraoanu, Becker-Roeck, Christ, Layer, Ernsberger, Esposito, Partimo, Huber, Franke, Bixby, Kalcheim, Unsicker,

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Disease relevance of NRXN1

As shown by ISH, Nx-1 is expressed in the inner half retina along with differentiation of ganglion and amacrine cells [1].

High impact information on NRXN1

Therefore, we studied the expression patterns of neurexin-1 (Nx-1) and neuroligin-1 and -3 during embryonic development of the chick retina and brain by reverse-transcriptase polymerase chain reaction (RT-PCR) and in situ hybridization (ISH) [1].
Expression patterns of neurexin-1 and neuroligins in brain and retina of the chick embryo: Neuroligin-3 is absent in retina [1].
Two additional neuronal markers, synaptotagmin 1 and neurexin 1, are expressed at low to undetectable levels in developing chromaffin cells throughout embryogenesis [2].

References

Expression patterns of neurexin-1 and neuroligins in brain and retina of the chick embryo: Neuroligin-3 is absent in retina. Paraoanu, L.E., Becker-Roeck, M., Christ, E., Layer, P.G. Neurosci. Lett. (2006) [Pubmed]
Expression of neuronal markers suggests heterogeneity of chick sympathoadrenal cells prior to invasion of the adrenal anlagen. Ernsberger, U., Esposito, L., Partimo, S., Huber, K., Franke, A., Bixby, J.L., Kalcheim, C., Unsicker, K. Cell Tissue Res. (2005) [Pubmed]

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