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Gene Review

TIMP3  -  TIMP metallopeptidase inhibitor 3

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High impact information on TIMP3

  • Role of the 21-kDa protein TIMP-3 in oncogenic transformation of cultured chicken embryo fibroblasts [1].
  • The cDNA of the 21-kDa protein was recently cloned, and based upon its deduced amino acid sequence and other supporting data we propose that it is another member of this family, a TIMP-3 [1].
  • TIMP-3 mRNA is expressed only in the notochord at stage 8 and later in the outflow tract myocardium [2].
  • Here, we examine the distribution of tissue inhibitor of metalloproteinase (TIMP) -2 and TIMP-3 and test whether manipulating TIMP levels alters chicken cardiac NC cell migration [2].
  • Upon hybridization with a panel of human-hamster somatic cell hybrid DNAs, the TIMP3 gene segregated with clones containing chromosome 22 [3].

Other interactions of TIMP3


Analytical, diagnostic and therapeutic context of TIMP3


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