The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia

Table of contents

About

Terms

 

Gene Review: 

SCP2  -  sterol carrier protein 2

Gallus gallus

Synonyms: NSL-TP, SCP-2, SCP-X, SCPX
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on SCP2

  • A reduction in SCP2/SCPx gene expression was observed with follicular maturation, correlating with falling estrogen production [1].
  • The two SCP2/SCPx mRNAs were most abundant in granulosa cells from small follicles [1].
  • The 2.4-kb clone, isolated from a liver cDNA library by homology screening with a rat SCP2 cDNA, encodes a 58-kDa polypeptide, SCPx, which encompasses the sequence for SCP2 at its C-terminus [1].
  • In summary, we have documented (i) marked conservation of SCP2/SCPx structure across species and (ii) developmental and hormonal regulation of the mRNAs which encode proteins thought to be involved in lipid metabolism [1].
  • Sterol Carrier Protein 2, a protein thought to be involved in various aspects of intracellular sterol transport and metabolism, was studied in the small intestine and liver of chickens near hatching [2].
 

Analytical, diagnostic and therapeutic context of SCP2

  • Northern blot analysis of poly(A)+ RNA from different chicken tissues revealed two mRNA species, one of 2.5 kb, encoding SCPx, and one of 1.4 kb, presumably encoding SCP2 [1].

References

  1. Chicken sterol carrier protein 2/sterol carrier protein x: cDNA cloning reveals evolutionary conservation of structure and regulated expression. Pfeifer, S.M., Sakuragi, N., Ryan, A., Johnson, A.L., Deeley, R.G., Billheimer, J.T., Baker, M.E., Strauss, J.F. Arch. Biochem. Biophys. (1993) [Pubmed]
  2. Developmental regulation of sterol carrier protein 2 in chicken intestine and liver at time of hatching. Reinhart, M.P., Foglia, T.A., Cooke, P.H. Biochem. Biophys. Res. Commun. (1993) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities