High impact information on LOC397754

• These results demonstrate that Xenopus oocytes contain an annexin II (calpactin I) heavy chain mRNA with a distinct amino terminus and suggest that multiple annexin II isoforms may be expressed during amphibian embryogenesis and development [1].
• Northern blots show a 1.4-kilobase (kb) annexin II heavy chain transcript throughout oogenesis and in mature eggs [1].
• We have isolated cDNAs encoding annexin II (calpactin I) heavy chain homologues from a Xenopus oocyte cDNA library [1].
• Thus, tyrosine phosphorylation is probably not a general mode of regulation of AnxII function(s) [2].
• The deduced amino acid sequences show a high degree of conservation when compared to the sequences of mammalian and chicken AnxII [2].

Biological context of LOC397754

• Annexin II (AnxII) is one of the Ca(2+)-dependent membrane- and phospholipid-binding proteins (annexins) which are encoded by a multigene family [2].

Analytical, diagnostic and therapeutic context of LOC397754

• The cDNA cloning and sequence analysis revealed that two types of AnxII mRNA are expressed in X. laevis [2].

References