The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

pstS  -  phosphate ABC transporter periplasmic...

Escherichia coli UTI89

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of pstS

  • PhoB protein is the transcriptional activator for genes in the phosphate regulon of Escherichia coli, such as phoA and pstS, that are induced by phosphate deprivation [1].

High impact information on pstS

  • The reconstituted mutant RNA polymerase holoenzymes were severely defective in transcribing the pstS gene, one of the pho genes, whereas they were efficient in transcribing the PhoB-independent promoters [2].
  • The phosphorylation of PhoB protein occurred concurrently with the acquisition of the ability to activate transcription from the pstS promoter [1].
  • It binds specifically to the DNA fragment containing the promoter region of pstS [3].
  • Two specific transcripts were detected, a 4.7-kb polycistronic mRNA spanning the whole operon and a quantitatively dominating 1.2-kb mRNA representing the first gene, pstS [4].
  • This APEC fimbrial gene cluster, which we have termed stg, is a member of a distinct group of related fimbriae that are located in the glmS-pstS intergenic region of certain E. coli and S. enterica strains [5].


  1. Signal transduction in the phosphate regulon of Escherichia coli involves phosphotransfer between PhoR and PhoB proteins. Makino, K., Shinagawa, H., Amemura, M., Kawamoto, T., Yamada, M., Nakata, A. J. Mol. Biol. (1989) [Pubmed]
  2. Role of the sigma 70 subunit of RNA polymerase in transcriptional activation by activator protein PhoB in Escherichia coli. Makino, K., Amemura, M., Kim, S.K., Nakata, A., Shinagawa, H. Genes Dev. (1993) [Pubmed]
  3. Regulation of the phosphate regulon of Escherichia coli. Activation of pstS transcription by PhoB protein in vitro. Makino, K., Shinagawa, H., Amemura, M., Kimura, S., Nakata, A., Ishihama, A. J. Mol. Biol. (1988) [Pubmed]
  4. Transcription of the pst operon of Clostridium acetobutylicum is dependent on phosphate concentration and pH. Fischer, R.J., Oehmcke, S., Meyer, U., Mix, M., Schwarz, K., Fiedler, T., Bahl, H. J. Bacteriol. (2006) [Pubmed]
  5. Characterization of Stg fimbriae from an avian pathogenic Escherichia coli O78:K80 strain and assessment of their contribution to colonization of the chicken respiratory tract. Lymberopoulos, M.H., Houle, S., Daigle, F., Léveillé, S., Brée, A., Moulin-Schouleur, M., Johnson, J.R., Dozois, C.M. J. Bacteriol. (2006) [Pubmed]
WikiGenes - Universities