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Gene Review

tsl  -  torso-like

Drosophila melanogaster

Synonyms: CG6705, Dm-tsl, Dmel\CG6705, Torso-like protein, Tsl, ...
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High impact information on tsl

  • These results suggest that the tsl protein is the ligand that binds to the torso receptor [1].
  • At early blastoderm stage, tsl protein forms a symmetrical concentration gradient at the poles on the surface of the devitellinized embryo [1].
  • Moreover, mosaic analysis demonstrates that tsl expression is necessary only in subpopulations of follicle cells located at the poles of the oocyte [2].
  • Here we describe torso-like (tsl), the sixth member of the terminal gene class, and show that it is unique among these genes in that its expression is required in the somatic follicle cells rather than in the germ line [2].
  • Cell surface proteins Nasrat and Polehole stabilize the Torso-like extracellular determinant in Drosophila oogenesis [3].

Biological context of tsl


Other interactions of tsl

  • However, it is not well understood how this signal is generated, although it is known to depend on the activity of many genes such as torso-like (tsl) and trunk (trk) [6].
  • Unexpectedly, the terminal pathway gene torso-like is required for Bcd-dependent transcription [7].


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