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Gene Review:

AGRP - agouti related protein homolog (mouse)

Gallus gallus

Takeuchi, S. et al.

Takeuchi, Teshigawara, Takahashi,

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High impact information on AGRP

Most of those AGRP-expressing tissues have been demonstrated to express melanocortin 4 receptors and/or other subtypes of melanocortin receptor whose mammalian counterparts can bind AGRP [1].
To examine whether or not the peripheral melanocortin 4 receptor signaling could be regulated by AGRP, we cloned and localized the expression of the AGRP gene in the chicken [1].
RT-PCR analysis detected the AGRP mRNA in all tissues examined: the brain, adrenal gland, heart, liver, spleen, gonads, kidney, uropygial gland, skeletal muscle and adipose tissues [1].

Other interactions of AGRP

Interestingly, the skin also expressed the AGRP mRNA, where Agouti, another melanocortin receptor antagonist regulating hair pigmentation, is expressed in rodents [1].

References

Widespread expression of Agouti-related protein (AGRP) in the chicken: a possible involvement of AGRP in regulating peripheral melanocortin systems in the chicken. Takeuchi, S., Teshigawara, K., Takahashi, S. Biochim. Biophys. Acta (2000) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AGRP	Bos taurus
AGRP	Canis lupus familiaris
LOC100859622	Gallus gallus
AGRP	Homo sapiens
AGRP	Macaca mulatta
Agrp	Mus musculus
AGRP	Pan troglodytes
Agrp	Rattus norvegicus

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