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Gene Review

myo  -  myoglianin

Drosophila melanogaster

Synonyms: BcDNA:LD02307, CG1838, Dmel\CG1838, MYO, Myo, ...
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High impact information on myoglianin

  • Further we demonstrated that both myoglianin and its most closely related mammalian ligand, myostatin, interacted with a Wit and Baboon (Babo) type II-type I receptor complex to activate TGFbeta/activin-like signaling pathways [1].
  • We also show that the zygotic expression of a recently described Drosophila activin, which maps to the same interval 102 on chromosome 4 as myoglianin, is restricted to the developing central and peripheral nervous system [2].
  • Northern analysis shows that myoglianin is expressed throughout the Drosophila life cycle [2].
  • Between stages 11 and 14, myoglianin mRNA is exclusively detected in glial cells and their precursors [2].


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