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Gene Review:

GSS - glutathione synthetase

Canis lupus familiaris

Rathbun, W.B. et al., Marin, E. et al., Boudjema, K. et al.

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High impact information on GSS

The enzymes include the glutathione biosynthesis system consisting of gamma-glutamylcysteine synthetase and glutathione synthetase, as well as glutathione peroxidase, glutathione reductase and glutathione-S-transferase [1].
The glutathione synthesizing enzymes, gamma-glutamyl cysteinyl synthetase and glutathione synthetase, were found in all skeletal muscles studied in dogs [2].
The increase in tissue glutathione stimulated by GSH or other precursors was sensitive to the glutathione synthetase inhibitor, buthionine sulfoximine [3].

References

Glutathione metabolism in lenses of dogs and rabbits: activities of five enzymes. Rathbun, W.B., Sethna, S.S., Skelnik, D.L., Bistner, S.I. Exp. Eye Res. (1983) [Pubmed]
Enzymes of glutathione synthesis in dog skeletal muscles and their response to training. Marin, E., Kretzschmar, M., Arokoski, J., Hänninen, O., Klinger, W. Acta Physiol. Scand. (1993) [Pubmed]
Changes in glutathione concentration in hypothermically perfused dog kidneys. Boudjema, K., Lindell, S.L., Southard, J.H., Belzer, F.O. J. Lab. Clin. Med. (1991) [Pubmed]

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AgaP_AGAP000534	Anopheles gambiae str. PEST
GSH2	Arabidopsis thaliana
AGOS_ACR284C	Ashbya gossypii ATCC 10895
GSS	Bos taurus
gss-1	Caenorhabditis elegans
gss	Danio rerio
CG32495	Drosophila melanogaster
GS	Drosophila melanogaster
GSS	Gallus gallus
GSS	Homo sapiens
KLLA0F07557g	Kluyveromyces lactis NRRL Y-1140
MGG_06454	Magnaporthe oryzae 70-15
Gss	Mus musculus
NCU06191	Neurospora crassa OR74A
Os11g0642800	Oryza sativa Japonica Group
GSS	Pan troglodytes
Gss	Rattus norvegicus
GSH2	Saccharomyces cerevisiae S288c
gsa1	Schizosaccharomyces pombe 972h-
gss	Xenopus (Silurana) tropicalis

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