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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

DBH  -  dopamine beta-hydroxylase (dopamine beta...

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High impact information on DBH

  • The results indicate that in the cell-free system newly synthesized DBH undergoes glycosylation and incorporation into microsomal membranes without cleavage of the NH2-terminal signal sequence [1].
  • Translation of full-length DBH with microsomal membranes generated two glycosylated products (GH and GL) depending on the magnesium concentration [2].
 

Anatomical context of DBH

  • To investigate differences at the amino terminus, full-length rat DBH mRNA, translated in a cell-free system, produced a 66-kDa peptide [1].

References

  1. Glycosylation and membrane insertion of newly synthesized rat dopamine beta-hydroxylase in a cell-free system without signal cleavage. Feng, Z., Angeletti, R.H., Levin, B.E., Sabban, E.L. J. Biol. Chem. (1992) [Pubmed]
  2. Mutagenesis of rat dopamine beta-hydroxylase: examination in cell-free system. Feng, Z., Sabban, E.L. J. Neurochem. (1995) [Pubmed]
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