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Gene Review

bur  -  burgundy

Drosophila melanogaster

Synonyms: CG9242, Dmel\CG9242, ES2-2, GMPS, Gmps, ...
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Disease relevance of bur


High impact information on bur

  • In a search for genes required for the establishment of neuronal connectivity in the fly visual system, we identify the burgundy (bur) gene as an essential player in photoreceptor axon guidance [1].
  • Guanosine supplements mutations at the burgundy locus (55.7); this locus was described previously through a pteridine eye-color defect but identified as an auxotrophic locus after the isolation of a new allele, burgua2-1 [2].


  1. De novo GMP synthesis is required for axon guidance in Drosophila. Long, H., Cameron, S., Yu, L., Rao, Y. Genetics (2006) [Pubmed]
  2. Three purine auxotrophic loci on the second chromosome of Drosophila melanogaster. Johnstone, M.E., Nash, D., Naguib, F.N. Biochem. Genet. (1985) [Pubmed]
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