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Gene Review

mod(mdg4)  -  modifier of mdg4

Drosophila melanogaster

Synonyms: BcDNA:GH07769, BcDNA:SD03001, CG15500, CG15501, CG15802, ...
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Disease relevance of mod(mdg4)


High impact information on mod(mdg4)


Biological context of mod(mdg4)

  • Thus, IAPs might block apoptosis by interacting with and modifying the behavior of Doom-like proteins that reside in cellular apoptotic pathways [1].

Anatomical context of mod(mdg4)

  • Ultrastructural characterization of synaptic boutons in bpd demonstrated abnormal layering of the postsynaptic specialization or subsynaptic reticulum (SSR) [4].
  • Synaptic terminals in bpd mutants developed abnormally, forming multiple branch points, overgrowing to inappropriate neighboring muscles, and establishing aberrant folding of postsynaptic membranes [4].

Associations of mod(mdg4) with chemical compounds

  • The baculoviral BIR and RING finger regions, when separated, were unable to block apoptosis induced by actinomycin D or Doom [3].


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