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Gene Review

DIO3  -  deiodinase, iodothyronine, type III

Bos taurus

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High impact information on DIO3


Biological context of DIO3

  • Sequencing of bovine DIO2 and DIO3 cDNAs revealed a high degree of predicted amino acid sequence identity with their orthologs in other mammalian species and demonstrated the conservation of selenocysteine residues within the catalytic domains of both bovine proteins [1].

Other interactions of DIO3

  • The goal of this study was to sequence the full-length bovine type II deiodinase (DIO2) and type III deiodinase (DIO3) cDNAs and characterize mRNA expression levels of each of the three deiodinase isoforms in several bovine tissues [1].


  1. Molecular cloning, expression and radiation hybrid mapping of the bovine deiodinase type II (DIO2) and deiodinase type III (DIO3) genes. Connor, E.E., Laiakis, E.C., Fernandes, V.M., Williams, J.L., Capuco, A.V. Anim. Genet. (2005) [Pubmed]
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