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MBD2  -  methyl-CpG binding domain protein 2

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High impact information on MBD2

  • These results represent the first purification of a MeCP1-like complex from a primary cell source and provide support for a role for MBD2 in developmental gene regulation [1].
  • Knock-down of MBD2 resulted in up-regulation of a methylated rho-gene construct in mouse erythroleukemic (MEL)-rho cells [1].
  • MBD2 is a critical component of a methyl cytosine-binding protein complex isolated from primary erythroid cells [1].

References

  1. MBD2 is a critical component of a methyl cytosine-binding protein complex isolated from primary erythroid cells. Kransdorf, E.P., Wang, S.Z., Zhu, S.Z., Langston, T.B., Rupon, J.W., Ginder, G.D. Blood (2006) [Pubmed]
 
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