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Gene Review

IGK  -  immunoglobulin kappa locus

Homo sapiens

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  1. A novel alteration in the structure of an activated c-myc gene in a variant t(2;8) Burkitt lymphoma. Taub, R., Kelly, K., Battey, J., Latt, S., Lenoir, G.M., Tantravahi, U., Tu, Z., Leder, P. Cell (1984) [Pubmed]
  2. The human immunoglobulin kappa locus. Characterization of the duplicated O regions. Pargent, W., Meindl, A., Thiebe, R., Mitzel, S., Zachau, H.G. Eur. J. Immunol. (1991) [Pubmed]
  3. Regulatory elements in the immunoglobulin kappa locus induce c-myc activation and the promoter shift in Burkitt's lymphoma cells. Polack, A., Feederle, R., Klobeck, G., Hörtnagel, K. EMBO J. (1993) [Pubmed]
  4. Transposition of human immunoglobulin V kappa genes within the same chromosome and the mechanism of their amplification. Zimmer, F.J., Hameister, H., Schek, H., Zachau, H.G. EMBO J. (1990) [Pubmed]
  5. The immunoglobulin kappa locus contains a second, stronger B-cell-specific enhancer which is located downstream of the constant region. Meyer, K.B., Neuberger, M.S. EMBO J. (1989) [Pubmed]
  6. The gene encoding the T-cell surface protein T4 is located on human chromosome 12. Isobe, M., Huebner, K., Maddon, P.J., Littman, D.R., Axel, R., Croce, C.M. Proc. Natl. Acad. Sci. U.S.A. (1986) [Pubmed]
  7. Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes. Kawasaki, K., Minoshima, S., Nakato, E., Shibuya, K., Shintani, A., Asakawa, S., Sasaki, T., Klobeck, H.G., Combriato, G., Zachau, H.G., Shimizu, N. Eur. J. Immunol. (2001) [Pubmed]
  8. Polymorphisms and haplotypes in the human immunoglobulin kappa locus. Pargent, W., Schäble, K.F., Zachau, H.G. Eur. J. Immunol. (1991) [Pubmed]
  9. The immunoglobulin kappa locus-or-what has been learned from looking closely at one-tenth of a percent of the human genome. Zachau, H.G. Gene (1993) [Pubmed]
  10. The human immunoglobulin kappa locus on yeast artificial chromosomes (YACs). Brensing-Küppers, J., Zocher, I., Thiebe, R., Zachau, H.G. Gene (1997) [Pubmed]
  11. Crosslinking of the cell surface immunoglobulin (mu-surrogate light chains complex) on pre-B cells induces activation of V gene rearrangements at the immunoglobulin kappa locus. Tsubata, T., Tsubata, R., Reth, M. Int. Immunol. (1992) [Pubmed]
  12. The CD8 alpha locus is located on the telomere side of the immunoglobulin kappa locus at a distance of 2 Mb. Weichhold, G.M., Huber, C., Parnes, J.R., Zachau, H.G. Genomics (1993) [Pubmed]
  13. The human T cell antigen Leu-2 (T8) is encoded on chromosome 2. Bruns, G., Kavathas, P., Shiloh, Y., Sakai, K., Schwaber, J., Latt, S.A., Herzenberg, L.A. Hum. Genet. (1985) [Pubmed]
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