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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

BET1L  -  Bet1 golgi vesicular membrane trafficking...

Homo sapiens

Synonyms: BET1-like protein, BET1L1, GOLIM3, GOS-15, GS15, ...
 
 
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Disease relevance of BET1L

  • Solids were collected from a culture of Geobacter metallireducens (GS-15) thatwas incubated with ferrihydrite (as the electron acceptor) for 0, 7, 10, 20, 75, and 400 days [1].
  • The reduction kinetics of Fe(III)citrate, Fe(III)NTA, Co(III)EDTA-, U(VI)O(2) (2+), Cr(VI)O(4) (2-), and Tc(VII)O(4) (-) were studied in cultures of dissimilatory metal reducing bacteria (DMRB): Shewanella alga strain BrY, Shewanella putrefaciens strain CN32, Shewanella oneidensis strain MR-1, and Geobacter metallireducens strain GS-15 [2].
 

High impact information on BET1L

  • In our present study, it is revealed that unlike proteins (Bet1 and the KDEL receptor) cycling between the Golgi and the intermediate compartment (IC, inclusive of the ER exit sites), GS15 is not redistributed into the IC upon incubation at 15 degrees C or when cells are treated with brefeldin A [3].
  • In order to identify important promoter elements controlling the ammonium-regulated expression of the soybean gene GS15 encoding cytosolic glutamine synthetase, a series of 5' promoter deletions were fused to the GUS reporter gene [4].
 

Analytical, diagnostic and therapeutic context of BET1L

References

  1. Hexahydro-1,3,5-trinitro-1,3,5-triazine transformation by biologically reduced ferrihydrite: evolution of Fe mineralogy, surface area, and reaction rates. Williams, A.G., Gregory, K.B., Parkin, G.F., Scherer, M.M. Environ. Sci. Technol. (2005) [Pubmed]
  2. Reduction kinetics of Fe(III), Co(III), U(VI), Cr(VI), and Tc(VII) in cultures of dissimilatory metal-reducing bacteria. Liu, C., Gorby, Y.A., Zachara, J.M., Fredrickson, J.K., Brown, C.F. Biotechnol. Bioeng. (2002) [Pubmed]
  3. GS15 forms a SNARE complex with syntaxin 5, GS28, and Ykt6 and is implicated in traffic in the early cisternae of the Golgi apparatus. Xu, Y., Martin, S., James, D.E., Hong, W. Mol. Biol. Cell (2002) [Pubmed]
  4. A strong constitutive positive element is essential for the ammonium-regulated expression of a soybean gene encoding cytosolic glutamine synthetase. Tercé-Laforgue, T., Carrayol, E., Cren, M., Desbrosses, G., Hecht, V., Hirel, B. Plant Mol. Biol. (1999) [Pubmed]
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