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cyp26c1  -  cytochrome P450, family 26, subfamily C,...

Danio rerio

Synonyms: SO:0000704, cyp26b1l, cyp26d1
 
 
 
 
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High impact information on cyp26c1

  • These alterations were similar to those caused by the overexpression of cyp26a1 in zebrafish embryos and to that which resulted from treating embryos with 1 microm 4-diethylamino-benzaldehyde (retinal dehydrogenase inhibitor), implying that cyp26d1 can antagonize RA activity in vivo [1].
  • Double in situ hybridization with krox20 and cyp26d1 reveals that cyp26d1 is expressed in presumptive rhombomere 2-4 (r2-r4) at 2-somite stage [2].
  • During segmentation period, cyp26d1 message is found at presumptive hindbrain [2].
  • At 3-somite stage, cyp26d1 gene is expressed in r6 and pharyngeal arch (pa) one in addition to its expression at r2 and r4 [2].
  • At 21-somite stage, cyp26d1 is also found in a group of cells in telencephalon and diencephalons [2].
 

Analytical, diagnostic and therapeutic context of cyp26c1

References

  1. A novel cytochrome P450, zebrafish Cyp26D1, is involved in metabolism of all-trans retinoic acid. Gu, X., Xu, F., Song, W., Wang, X., Hu, P., Yang, Y., Gao, X., Zhao, Q. Mol. Endocrinol. (2006) [Pubmed]
  2. Molecular cloning and expression of a novel CYP26 gene (cyp26d1) during zebrafish early development. Gu, X., Xu, F., Wang, X., Gao, X., Zhao, Q. Gene Expr. Patterns (2005) [Pubmed]
 
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