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Gene Review

PITPNM2  -  phosphatidylinositol transfer protein,...

Homo sapiens

Synonyms: KIAA1457, Membrane-associated phosphatidylinositol transfer protein 2, NIR-3, NIR3, PITPnm 2, ...
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Disease relevance of PITPNM2

  • In contrast, Nir2 and Nir3 were homogeneously distributed in undifferentiated neuroblasts and ganglion cells at birth and later became distinctly distributed in newly differentiated neuronal cells [1].

High impact information on PITPNM2

  • In the adult rat retina, Nir2 was preferentially localized to the somata of all classes of retinal neurons, whereas Nir3 was highly expressed in the synaptic terminals [1].

Biological context of PITPNM2


Anatomical context of PITPNM2

  • In photoreceptor cells, both Nir2 and Nir3 were found to be highly expressed in the inner segments but were not detectably expressed in the outer segments [1].


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