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Gene Review

SH3RF1  -  SH3 domain containing ring finger 1

Homo sapiens

Synonyms: E3 ubiquitin-protein ligase SH3RF1, KIAA1494, POSH, Plenty of SH3s, Protein POSH, ...
 
 
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Disease relevance of SH3RF1

 

High impact information on SH3RF1

  • Reintroduction of native, but not a RING finger mutant, hPOSH restores virus release and Gag plasma membrane localization in hPOSH-depleted cells [1].
 

Anatomical context of SH3RF1

References

  1. The trans-Golgi network-associated human ubiquitin-protein ligase POSH is essential for HIV type 1 production. Alroy, I., Tuvia, S., Greener, T., Gordon, D., Barr, H.M., Taglicht, D., Mandil-Levin, R., Ben-Avraham, D., Konforty, D., Nir, A., Levius, O., Bicoviski, V., Dori, M., Cohen, S., Yaar, L., Erez, O., Propheta-Meiran, O., Koskas, M., Caspi-Bachar, E., Alchanati, I., Sela-Brown, A., Moskowitz, H., Tessmer, U., Schubert, U., Reiss, Y. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  2. Breast cancer awareness: Star, Posh, Hot and Prime. Foss, T.D. British journal of nursing (Mark Allen Publishing) (2006) [Pubmed]
 
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