The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

SH3RF1  -  SH3 domain containing ring finger 1

Homo sapiens

Synonyms: E3 ubiquitin-protein ligase SH3RF1, KIAA1494, POSH, Plenty of SH3s, Protein POSH, ...
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of SH3RF1


High impact information on SH3RF1

  • Reintroduction of native, but not a RING finger mutant, hPOSH restores virus release and Gag plasma membrane localization in hPOSH-depleted cells [1].

Anatomical context of SH3RF1


  1. The trans-Golgi network-associated human ubiquitin-protein ligase POSH is essential for HIV type 1 production. Alroy, I., Tuvia, S., Greener, T., Gordon, D., Barr, H.M., Taglicht, D., Mandil-Levin, R., Ben-Avraham, D., Konforty, D., Nir, A., Levius, O., Bicoviski, V., Dori, M., Cohen, S., Yaar, L., Erez, O., Propheta-Meiran, O., Koskas, M., Caspi-Bachar, E., Alchanati, I., Sela-Brown, A., Moskowitz, H., Tessmer, U., Schubert, U., Reiss, Y. Proc. Natl. Acad. Sci. U.S.A. (2005) [Pubmed]
  2. Breast cancer awareness: Star, Posh, Hot and Prime. Foss, T.D. British journal of nursing (Mark Allen Publishing) (2006) [Pubmed]
WikiGenes - Universities