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Esm1  -  endothelial cell-specific molecule 1

Rattus norvegicus

Synonyms: ESM-1, Endothelial cell-specific molecule 1, PG25
 
 
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High impact information on Esm1

  • Suckling rats were treated every 8 h by intragastric instillation of 16,16-dimethyl prostaglandin E2 (PG) in a dose of 25 micrograms kg-1 (PG25), or 100 micrograms kg-1 (PG100), or saline from postnatal day 7-11 [1].
  • Eight hours after both the last PG25 and the last PG100 dose, plasma gastrin and corticosterone levels were decreased while thyroxine remained unchanged [1].
  • PG increased small intestinal villus length and crypt depth, most markedly in the duodenum, leading to a mucosal height of 543 +/- 24 microns after saline, 670 +/- 26 microns after PG25 and 823 +/- 40 microns after PG100 [1].
 

Analytical, diagnostic and therapeutic context of Esm1

  • PG25, a pineal-specific cDNA, cloned by differential display PCR (DDPCR) and rapid amplification of cDNA ends (RACE) [2].

References

  1. Effect of 16,16-dimethyl prostaglandin E2 on small intestinal mucosa in suckling rats. Koelz, H.R., Lentze, M.J., Müller, O.M., Halter, F. Eur. J. Clin. Invest. (1987) [Pubmed]
  2. PG25, a pineal-specific cDNA, cloned by differential display PCR (DDPCR) and rapid amplification of cDNA ends (RACE). Wang, X., Brownstein, M.J., Young, W.S. J. Neurosci. Methods (1997) [Pubmed]
 
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