Gene Review:
Gast - gastrin
Rattus norvegicus
Synonyms:
Gas, Gastrin, PPG34
- Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor. Guo, Y.S., Cheng, J.Z., Jin, G.F., Gutkind, J.S., Hellmich, M.R., Townsend, C.M. J. Biol. Chem. (2002)
- Relative potencies of the somatostatin analogs octreotide, BIM-23014, and RC-160 on the inhibition of hormone release by cultured human endocrine tumor cells and normal rat anterior pituitary cells. Hofland, L.J., van Koetsveld, P.M., Waaijers, M., Zuyderwijk, J., Lamberts, S.W. Endocrinology (1994)
- Intracellular mechanisms mediating the anti-apoptotic action of gastrin. Ramamoorthy, S., Stepan, V., Todisco, A. Biochem. Biophys. Res. Commun. (2004)
- Hypogastrinemia in streptozotocin diabetes with islet transplantation--reconstitution. Fabri, P.J., Weber, C.J., Gower, W.R., Reemtsma, K. J. Surg. Res. (1983)
- Effect of high temperature on gastrin, somatostatin and motilin production in ulcerous gastric antral mucosa of rats. Sun, F.P., Dan, H.L., Song, Y.G., Cheng, W. Di Yi Jun Yi Da Xue Xue Bao (2002)
- Effect of food deprivation on rat gastric somatostatin and gastrin release. Koop, H., Schwab, E., Arnold, R., Creutzfeldt, W. Gastroenterology (1982)
- Partial sleep deprivation compromises gastric mucosal integrity in rats. Guo, J.S., Chau, J.F., Cho, C.H., Koo, M.W. Life Sci. (2005)
- Physiological role of cholecystokinin B/gastrin receptor in leptin secretion. Attoub, S., Levasseur, S., Buyse, M., Goïot, H., Laigneau, J.P., Moizo, L., Hervatin, F., Le Marchand-Brustel, Y., Lewin, J.M., Bado, A. Endocrinology (1999)
- Serum gastrin increases with increasing dietary calcium but not with increasing dietary fat or fiber in Fischer-344 rats. Floor, M.K., Jahangeer, S., D'Ambrosio, C., Alabaster, O. J. Nutr. (1991)
- Histamine in stress ulcer prophylaxis in rats. Warzecha, Z., Dembiński, A., Brzozowski, T., Ceranowicz, P., Dembiński, M., Stachura, J., Konturek, S.J. J. Physiol. Pharmacol. (2001)
- Complete tyrosine-O-sulphation of gastrin in neonatal rat pancreas. Brand, S.J., Andersen, B.N., Rehfeld, J.F. Nature (1984)
- GABA affects the release of gastrin and somatostatin from rat antral mucosa. Harty, R.F., Franklin, P.A. Nature (1983)
- Localization of targets for anti-ulcer drugs in cells of the immune system. Mezey, E., Palkovits, M. Science (1992)
- Reciprocal regulation of antral gastrin and somatostatin gene expression by omeprazole-induced achlorhydria. Brand, S.J., Stone, D. J. Clin. Invest. (1988)
- Peptide YY inhibition of rat gastric enterochromaffin-like cell function. Zeng, N., Walsh, J.H., Kang, T., Wu, S.V., Sachs, G. Gastroenterology (1997)
- Helicobacter pylori lipopolysaccharide stimulates histamine release and DNA synthesis in rat enterochromaffin-like cells. Kidd, M., Miu, K., Tang, L.H., Perez-Perez, G.I., Blaser, M.J., Sandor, A., Modlin, I.M. Gastroenterology (1997)
- Influence of chronic drug-induced achlorhydria by substituted benzimidazoles on the endocrine stomach in rats. Koop, H., Willemer, S., Steinbach, F., Eissele, R., Tuch, K., Arnold, R. Gastroenterology (1987)
- Differential gastrin gene expression in rat gastrointestinal tract and pancreas during neonatal development. Brand, S.J., Fuller, P.J. J. Biol. Chem. (1988)
- Processing of the gastrin precursor. Modulation of phosphorylated, sulfated, and amidated products. Varro, A., Nemeth, J., Bridson, J., Lee, C., Moore, S., Dockray, G.J. J. Biol. Chem. (1990)
- Molecular cloning and sequencing of a rat preprogastrin complementary deoxyribonucleic acid. Fuller, P.J., Stone, D.L., Brand, S.J. Mol. Endocrinol. (1987)
- Intracellular signal transduction during gastrin-induced histamine secretion in rat gastric ECL cells. Zanner, R., Hapfelmeier, G., Gratzl, M., Prinz, C. Am. J. Physiol., Cell Physiol. (2002)
- Somatostatin receptor subtype 2 mediates inhibition of gastrin and histamine secretion from human, dog, and rat antrum. Zaki, M., Harrington, L., McCuen, R., Coy, D.H., Arimura, A., Schubert, M.L. Gastroenterology (1996)
- Sucrose octasulfate stimulates gastric somatostatin release. Lucey, M.R., Park, J., DelValle, J., Wang, L.D., Yamada, T. Am. J. Med. (1991)
- Somatostatin inhibition of basal and carbachol-stimulated gastrin release in rat antral organ culture. Harty, R.F., Maico, D.G., McGuigan, J.E. Gastroenterology (1981)
- The effect of pentagastrin on the somatostatin receptor/effector system in rat pancreatic acinar membranes. Alvaro-Alonso, I., Muñoz-Acedo, G., Arilla, E. Regul. Pept. (1994)
- Synthesis and biological evaluation of a new reversely linked type of dual histamine H2 and gastrin receptor antagonist. Kawanishi, Y., Ishihara, S., Takahashi, K., Tsushima, T., Hagishita, S., Ishikawa, M., Ishihara, Y. Chem. Pharm. Bull. (1997)
- Involvement of JAK2 upstream of the PI 3-kinase in cell-cell adhesion regulation by gastrin. Ferrand, A., Kowalski-Chauvel, A., Bertrand, C., Pradayrol, L., Fourmy, D., Dufresne, M., Seva, C. Exp. Cell Res. (2004)
- Gastrin enhances gastric mucosal integrity through cyclooxygenase-2 upregulation in rats. Komori, M., Tsuji, S., Sun, W.H., Tsujii, M., Kawai, N., Yasumaru, M., Kakiuchi, Y., Kimura, A., Sasaki, Y., Higashiyama, S., Kawano, S., Hori, M. Am. J. Physiol. Gastrointest. Liver Physiol. (2002)
- Molecular mechanisms for the antiapoptotic action of gastrin. Todisco, A., Ramamoorthy, S., Witham, T., Pausawasdi, N., Srinivasan, S., Dickinson, C.J., Askari, F.K., Krametter, D. Am. J. Physiol. Gastrointest. Liver Physiol. (2001)
- Role of neuropeptide-sensitive L-type Ca(2+) channels in histamine release in gastric enterochromaffin-like cells. Zeng, N., Athmann, C., Kang, T., Walsh, J.H., Sachs, G. Am. J. Physiol. (1999)
- Somatostatin, misoprostol and galanin inhibit gastrin- and PACAP-stimulated secretion of histamine and pancreastatin from ECL cells by blocking specific Ca2+ channels. Björkqvist, M., Bernsand, M., Eliasson, L., Håkanson, R., Lindström, E. Regul. Pept. (2005)
- Evaluation of the effects of pentagastrin, gastrin and pancreatic glucagon on cell proliferation in the rat gastrointestinal tract. Fatemi, S.H., Cullan, G.E., Sharp, J.G. Cell and tissue kinetics. (1984)
- Topography of somatostatin cells in the stomach of the rat: possible functional significance. Alumets, J., Ekelund, M., El Munshid, H.A., Håkanson, R., Lorén, I., Sundler, F. Cell Tissue Res. (1979)
- Gastric inhibitory polypeptide and glucagon-like peptide-1(7-36) amide exert similar effects on somatostatin secretion but opposite effects on gastrin secretion from the rat stomach. Jia, X., Brown, J.C., Kwok, Y.N., Pederson, R.A., McIntosh, C.H. Can. J. Physiol. Pharmacol. (1994)
- Mucus, gastrin and somatostatin cells in cultured rat antral mucosa: immunofluorescence, ultrastructural and radioimmunological studies. Sahondramanarivo, G., Hollande, E., Pequignot, J., Accary, J.P., Dubrasquet, J.M. Gastroenterol. Clin. Biol. (1986)