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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Pcgf3  -  polycomb group ring finger 3

Mus musculus

Synonyms: 2310035N15Rik, AI662857, D630042K08Rik, DONG1, E430039C14, ...
 
 
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Disease relevance of Pcgf3

  • A popular Chinese herb, Angelica sinensis (also known as Dang Gui or Dong Quai) has been used traditionally for treating women with gynecological disorders (such as dysmenorrheal and hot flashes) [1].
 

High impact information on Pcgf3

  • Our previous study showed that mitogen-activated protein kinases MAP kinases are involved in ultraviolet B-induced phosphorylation of histone H3 at serine 28 (Zhong, S., Zhong, Z., Jansen, J., Goto, H., Inagaki, M., and Dong, Z., J. Biol. Chem. 276, 12932-12937) [2].
  • In this study, we investigate the estrogenic activity of four selected herbs commonly used in menopause, namely dong quai, ginseng, black cohosh, and licorice root [3].
  • A murine endothelial cell line was recently established from microvessels that had invaded a subcutaneous sponge implant (Dong, Q. G.; Bernasconi, S.; Lostaglio, S., et al. Arterioscl. Thromb. Vasc. Biol. 17:1599-1604; 1997) [4].

References

  1. The aqueous extract of a popular herbal nutrient supplement, Angelica sinensis, protects mice against lethal endotoxemia and sepsis. Wang, H., Li, W., Li, J., Rendon-Mitchell, B., Ochani, M., Ashok, M., Yang, L., Yang, H., Tracey, K.J., Wang, P., Sama, A.E. J. Nutr. (2006) [Pubmed]
  2. Ultraviolet B-induced phosphorylation of histone H3 at serine 28 is mediated by MSK1. Zhong, S., Jansen, C., She, Q.B., Goto, H., Inagaki, M., Bode, A.M., Ma, W.Y., Dong, Z. J. Biol. Chem. (2001) [Pubmed]
  3. Estrogenic activity of herbs commonly used as remedies for menopausal symptoms. Amato, P., Christophe, S., Mellon, P.L. Menopause (New York, N.Y.) (2002) [Pubmed]
  4. Characterization of novel clonal murine endothelial cell lines with an extended life span. Cavallaro, U., Castelli, V., Perilli, A., Dossi, R., Giavazzi, R., Pepper, M.S., Soria, M.R., Montesano, R. In Vitro Cell. Dev. Biol. Anim. (2000) [Pubmed]
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