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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ADF1  -  actin depolymerizing factor 1

Arabidopsis thaliana

Synonyms: ATADF1, atadf
 
 
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High impact information on ADF1

  • In contrast, reduced AtADF expression promoted the formation of actin cables, resulted in a delay in flowering, and stimulated cell expansion as well as organ growth [1].
  • One protein that is conserved across phylogeny is actin-depolymerizing factor or cofilin and we describe our work on the activity of vegetative tissue and pollen-specific isoforms of this protein in plant cells, concluding that they are functionally distinct [2].
  • Petunia actin-depolymerizing factor is mainly accumulated in vascular tissue and its gene expression is enhanced by the first intron [3].
  • Molecular identification and characterization of the Arabidopsis AtADF1, AtADFS and AtADF6 genes [4].
 

Biological context of ADF1

  • Overexpression of AtADF1 resulted in the disappearance of thick actin cables in different cell types, caused irregular cellular and tissue morphogenesis, and reduced the growth of cells and organs [1].
 

Anatomical context of ADF1

References

  1. ADF proteins are involved in the control of flowering and regulate F-actin organization, cell expansion, and organ growth in Arabidopsis. Dong, C.H., Xia, G.X., Hong, Y., Ramachandran, S., Kost, B., Chua, N.H. Plant Cell (2001) [Pubmed]
  2. Actin-binding proteins in the Arabidopsis genome database: properties of functionally distinct plant actin-depolymerizing factors/cofilins. Hussey, P.J., Allwood, E.G., Smertenko, A.P. Philos. Trans. R. Soc. Lond., B, Biol. Sci. (2002) [Pubmed]
  3. Petunia actin-depolymerizing factor is mainly accumulated in vascular tissue and its gene expression is enhanced by the first intron. Mun, J.H., Lee, S.Y., Yu, H.J., Jeong, Y.M., Shin, M.Y., Kim, H., Lee, I., Kim, S.G. Gene (2002) [Pubmed]
  4. Molecular identification and characterization of the Arabidopsis AtADF1, AtADFS and AtADF6 genes. Dong, C.H., Kost, B., Xia, G., Chua, N.H. Plant Mol. Biol. (2001) [Pubmed]
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