The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Links

 

Gene Review

AT4G11310  -  putative cysteine proteinase

Arabidopsis thaliana

Synonyms: AtCP1, CP1, F8L21.100, F8L21_100, cysteine protease 1
 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on RD21

  • Using one-step affinity capture of biotinylated proteases followed by sequencing mass spectrometry, we identified proteases that include xylem-specific XCP2, desiccation-induced RD21, and cathepsin B- and aleurain-like proteases [1].
  • Arabidopsis RD21 is a cysteine protease of the papain family [2].
  • Subcellular fractionation of the Bright-Yellow 2 transformant showed that the intermediate and mature forms of RD21 were localized in the vacuoles [2].
  • Unlike other members of the papain family, RD21 has a C-terminal extension sequence composed of two domains, a 2-kD proline-rich domain and a 10-kD domain homologous to animal epithelin/granulin family proteins [2].
  • Taken together, these results indicate that the intermediate of RD21 was accumulated in the vacuoles as an aggregate, and then slowly matured to make a soluble protease by removing the granulin domain during leaf senescence [2].

References

  1. Activity profiling of papain-like cysteine proteases in plants. van der Hoorn, R.A., Leeuwenburgh, M.A., Bogyo, M., Joosten, M.H., Peck, S.C. Plant Physiol. (2004) [Pubmed]
  2. A slow maturation of a cysteine protease with a granulin domain in the vacuoles of senescing Arabidopsis leaves. Yamada, K., Matsushima, R., Nishimura, M., Hara-Nishimura, I. Plant Physiol. (2001) [Pubmed]
 
WikiGenes - Universities