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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Cstf2t  -  cleavage stimulation factor, 3' pre-RNA...

Mus musculus

Synonyms: 64kDa, C77975, CF-1 64 kDa subunit tau variant, CSTF 64 kDa subunit tau variant, Cleavage stimulation factor 64 kDa subunit tau variant, ...
 
 
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High impact information on Cstf2t

  • Developmental distribution of the polyadenylation protein CstF-64 and the variant tauCstF-64 in mouse and rat testis [1].
  • The second form, tauCstF-64 (encoded by the autosomal gene Cstf2t), is expressed in a more limited set of tissues and cell types, largely in meiotic and postmeiotic male germ cells and, to a smaller extent, in brain [1].
  • Therefore, we were surprised to find that, using reverse transcription-PCR, cDNA cloning, and RNA blot analyses, tauCstF-64 mRNA was expressed at higher levels in brain than in testis [2].
  • Also, tauCstF-64 mRNA was expressed at lower but detectable levels in all tissues tested, including epididymis, heart, kidney, liver, lung, muscle, ovary, spleen, thymus, and uterus [2].

References

  1. Developmental distribution of the polyadenylation protein CstF-64 and the variant tauCstF-64 in mouse and rat testis. Wallace, A.M., Denison, T.L., Attaya, E.N., MacDonald, C.C. Biol. Reprod. (2004) [Pubmed]
  2. The mRNA encoding tauCstF-64 is expressed ubiquitously in mouse tissues. Huber, Z., Monarez, R.R., Dass, B., MacDonald, C.C. Ann. N. Y. Acad. Sci. (2005) [Pubmed]
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