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Gene Review

ZLL  -  eIF2C family protein Argonaute10

Arabidopsis thaliana

Synonyms: AGO10, ARGONAUTE 10, ARGONAUTE PROTEIN 10, MQD19.17, MQD19_17, ...
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High impact information on ZLL


Associations of ZLL with chemical compounds


Biological context of ZLL

  • Using specific antibodies against ZLL, we show that the zll phenotype is due to the complete absence of the ZLL protein [7].
  • These results also indicate that genes regulating cell division and axis determinacy are likely to be among PNH targets [3].

Other interactions of ZLL

  • Mutant and marker gene analyses suggest that during shoot meristem formation, ZLL functions in a similar manner but in a sequential order with its close homologue AGO1, which mediates RNA interference [8].


  1. Role of the ZWILLE gene in the regulation of central shoot meristem cell fate during Arabidopsis embryogenesis. Moussian, B., Schoof, H., Haecker, A., Jürgens, G., Laux, T. EMBO J. (1998) [Pubmed]
  2. Fertile hypomorphic ARGONAUTE (ago1) mutants impaired in post-transcriptional gene silencing and virus resistance. Morel, J.B., Godon, C., Mourrain, P., Béclin, C., Boutet, S., Feuerbach, F., Proux, F., Vaucheret, H. Plant Cell (2002) [Pubmed]
  3. Regulation of axis determinacy by the Arabidopsis PINHEAD gene. Newman, K.L., Fernandez, A.G., Barton, M.K. Plant Cell (2002) [Pubmed]
  4. The effects of polyethylene glycol on gene expression of developing white spruce somatic embryos. Stasolla, C., van Zyl, L., Egertsdotter, U., Craig, D., Liu, W., Sederoff, R.R. Plant Physiol. (2003) [Pubmed]
  5. The SHOOT MERISTEMLESS gene is required for maintenance of undifferentiated cells in Arabidopsis shoot and floral meristems and acts at a different regulatory level than the meristem genes WUSCHEL and ZWILLE. Endrizzi, K., Moussian, B., Haecker, A., Levin, J.Z., Laux, T. Plant J. (1996) [Pubmed]
  6. ZLL/AGO10 maintains shoot meristem stem cells during Arabidopsis embryogenesis by down-regulating ARF2-mediated auxin response. Roodbarkelari, F., Du, F., Truernit, E., Laux, T. BMC Biol. (2015) [Pubmed]
  7. ZWILLE buffers meristem stability in Arabidopsis thaliana. Moussian, B., Haecker, A., Laux, T. Dev. Genes Evol. (2003) [Pubmed]
  8. Vascular signalling mediated by ZWILLE potentiates WUSCHEL function during shoot meristem stem cell development in the Arabidopsis embryo. Tucker, M.R., Hinze, A., Tucker, E.J., Takada, S., Jürgens, G., Laux, T. Development (2008) [Pubmed]
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