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Gene Review

MCM3  -  DNA replication licensing factor MCM3-like...

Arabidopsis thaliana

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High impact information on AT5G46280

  • Thus two highly similar E2F binding sites in the promoter of the MCM3 gene are responsible for different cell cycle regulation or developmental expression patterns depending on the cellular environment [1].
  • The Arabidopsis MCM3 homologue forms part of the mini chromosome maintenance (MCM) complex involved in the initiation of DNA replication at the transition G(1)/S [1].


  1. Two E2F sites in the Arabidopsis MCM3 promoter have different roles in cell cycle activation and meristematic expression. Stevens, R., Mariconti, L., Rossignol, P., Perennes, C., Cella, R., Bergounioux, C. J. Biol. Chem. (2002) [Pubmed]
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