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Gene Review:

TDT - tonoplast dicarboxylate transporter

Arabidopsis thaliana

Synonyms: ATSDAT, ATTDT, TONOPLAST DICARBOXYLATE TRANSPORTER

Hurth, M.A. et al., Emmerlich, V. et al.

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High impact information on ATSDAT/ATTDT

Vacuoles isolated from mutant plants import [14C]-malate at strongly reduced rates, confirming that this protein is the vacuolar malate transporter [1].
Arabidopsis (Arabidopsis thaliana) mutants lacking the tonoplastic malate transporter AttDT (A. thaliana tonoplast dicarboxylate transporter) and wild-type plants showed no phenotypic differences when grown under standard conditions [2].

Biological context of ATSDAT/ATTDT

In conclusion, these results show that Arabidopsis vacuoles contain at least two transporters and a channel for dicarboxylates and citrate and that the activity of AttDT is critical for regulation of pH homeostasis [2].

References

The plant homolog to the human sodium/dicarboxylic cotransporter is the vacuolar malate carrier. Emmerlich, V., Linka, N., Reinhold, T., Hurth, M.A., Traub, M., Martinoia, E., Neuhaus, H.E. Proc. Natl. Acad. Sci. U.S.A. (2003) [Pubmed]
Impaired pH homeostasis in Arabidopsis lacking the vacuolar dicarboxylate transporter and analysis of carboxylic acid transport across the tonoplast. Hurth, M.A., Suh, S.J., Kretzschmar, T., Geis, T., Bregante, M., Gambale, F., Martinoia, E., Neuhaus, H.E. Plant Physiol. (2005) [Pubmed]

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