Gene Review:
Indy - I'm not dead yet
Drosophila melanogaster
Synonyms:
BEST:LP01220, CG3979, Dmel\CG3979, INDY, INDY transporter protein, ...
- Functional characterization and immunolocalization of the transporter encoded by the life-extending gene Indy. Knauf, F., Rogina, B., Jiang, Z., Aronson, P.S., Helfand, S.L. Proc. Natl. Acad. Sci. U.S.A. (2002)
- Extended life-span conferred by cotransporter gene mutations in Drosophila. Rogina, B., Reenan, R.A., Nilsen, S.P., Helfand, S.L. Science (2000)
- An accelerated assay for the identification of lifespan-extending interventions in Drosophila melanogaster. Bauer, J.H., Goupil, S., Garber, G.B., Helfand, S.L. Proc. Natl. Acad. Sci. U.S.A. (2004)
- Conditional tradeoffs between aging and organismal performance of Indy long-lived mutant flies. Marden, J.H., Rogina, B., Montooth, K.L., Helfand, S.L. Proc. Natl. Acad. Sci. U.S.A. (2003)
- Structural and functional characteristics of two sodium-coupled dicarboxylate transporters (ceNaDC1 and ceNaDC2) from Caenorhabditis elegans and their relevance to life span. Fei, Y.J., Inoue, K., Ganapathy, V. J. Biol. Chem. (2003)
- No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects. Toivonen, J.M., Walker, G.A., Martinez-Diaz, P., Bjedov, I., Driege, Y., Jacobs, H.T., Gems, D., Partridge, L. PLoS. Genet. (2007)
- Longevity of Indy mutant Drosophila not attributable to Indy mutation. Toivonen, J.M., Gems, D., Partridge, L. Proc. Natl. Acad. Sci. U. S. A. (2009)
- Distinct genetic influences on locomotor senescence in Drosophila revealed by a series of metrical analyses. Martin, I., Grotewiel, M.S. Exp. Gerontol. (2006)
- Functional identity of Drosophila melanogaster Indy as a cation-independent, electroneutral transporter for tricarboxylic acid-cycle intermediates. Inoue, K., Fei, Y.J., Huang, W., Zhuang, L., Chen, Z., Ganapathy, V. Biochem. J. (2002)
- The life-extending gene Indy encodes an exchanger for Krebs-cycle intermediates. Knauf, F., Mohebbi, N., Teichert, C., Herold, D., Rogina, B., Helfand, S., Gollasch, M., Luft, F.C., Aronson, P.S. Biochem. J. (2006)
- Human sodium-coupled citrate transporter, the orthologue of Drosophila Indy, as a novel target for lithium action. Inoue, K., Zhuang, L., Maddox, D.M., Smith, S.B., Ganapathy, V. Biochem. J. (2003)
- Molecular properties of the SLC13 family of dicarboxylate and sulfate transporters. Pajor, A.M. Pflugers Arch. (2006)
- Functional features and genomic organization of mouse NaCT, a sodium-coupled transporter for tricarboxylic acid cycle intermediates. Inoue, K., Fei, Y.J., Zhuang, L., Gopal, E., Miyauchi, S., Ganapathy, V. Biochem. J. (2004)