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Gene Review

USP26  -  ubiquitin specific peptidase 26

Homo sapiens

Synonyms: Deubiquitinating enzyme 26, Ubiquitin carboxyl-terminal hydrolase 26, Ubiquitin thioesterase 26, Ubiquitin-specific-processing protease 26
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High impact information on USP26

  • The ubiquitin-specific protease 26 (USP26) gene is an X-linked gene specifically expressed in testis tissue [1].
  • Possible role of USP26 in patients with severely impaired spermatogenesis [1].
  • Dissolution studies were conducted (USP 26) using deionized water at 37+/-0.2 degrees C with paddle rotation of 50 rpm, and samples were removed manually at appropriate time intervals [2].
  • The cytotoxicity of chitosan was concentration dependent but almost molecular weight independent according to MTT assay using L929 cell line recommended by USP26 [3].
  • The dissolution test of Deprazolin tablets was programmed for 60 min, with a continuous sampling rate of 70 h(-1) under conditions required by USP 26 [4].

Associations of USP26 with chemical compounds


Analytical, diagnostic and therapeutic context of USP26

  • The results obtained from the analysis of commercial tablets were compared statistically with those obtained from the USP 26 high-performance liquid chromatographic (HPLC) method [6].


  1. Possible role of USP26 in patients with severely impaired spermatogenesis. Stouffs, K., Lissens, W., Tournaye, H., Van Steirteghem, A., Liebaers, I. Eur. J. Hum. Genet. (2005) [Pubmed]
  2. Development of a simple analytical methodology for determination of glucosamine release from modified release matrix tablets. Wu, Y., Hussain, M., Fassihi, R. Journal of pharmaceutical and biomedical analysis. (2005) [Pubmed]
  3. The depolymerization of chitosan: effects on physicochemical and biological properties. Mao, S., Shuai, X., Unger, F., Simon, M., Bi, D., Kissel, T. International journal of pharmaceutics. (2004) [Pubmed]
  4. Sensitive fluorimetric method based on sequential injection analysis technique used for dissolution studies and quality control of prazosin hydrochloride in tablets. Legnerová, Z., Huclová, J., Thun, R., Solich, P. Journal of pharmaceutical and biomedical analysis. (2004) [Pubmed]
  5. Quality control of tablets by Near Infrared (NIR)-Spectroscopy. Petri, J., Kaunzinger, A., Niemöller, A., Karas, M. Die Pharmazie. (2005) [Pubmed]
  6. Electrochemical study of hydrochlorothiazide and its determination in urine and tablets. Abdel Razak, O. Journal of pharmaceutical and biomedical analysis. (2004) [Pubmed]
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