High impact information on SDD1

• We propose that SDD1 acts as a processing protease involved in the mediation of a signal that controls the development of cell lineages that lead to guard cell formation [1].
• The SDD1 gene that encodes a subtilisin-like Ser protease is expressed strongly in stomatal precursor cells (meristemoids and guard mother cells), and the SDD1 promoter is controlled negatively by a feedback mechanism [2].
• Thus, we propose that SDD1 generates an extracellular signal by meristemoids/guard mother cells and demonstrate that the function of SDD1 is dependent on TMM activity [2].
• The subtilisin-like serine protease SDD1 mediates cell-to-cell signaling during Arabidopsis stomatal development [2].
• SDD1 overexpression in the wild type leads to a phenotype opposite to that caused by the sdd1-1 mutation, with a twofold to threefold decrease in stomatal density and the formation of arrested stomata [2].

Biological context of SDD1

• In the Arabidopsis mutant sdd1-1, a point mutation in a single gene (SDD1) causes specific alterations in stomatal density and distribution [3].

Analytical, diagnostic and therapeutic context of SDD1

• Molecular cloning of the SDD1 gene initiated the elucidation of the underlying molecular mechanisms [4].

References