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Gene Review:

PAB5 - polyadenylate-binding protein 5

Arabidopsis thaliana

Synonyms: F14O23.15, F14O23_15, POLY(A)-BINDING PROTEIN, poly(A)-binding protein 5

Belostotsky, D.A. et al., Belostotsky, D.A. et al.

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High impact information on PAB5

Here, we report that the expression of the PAB5 gene encoding one of the poly(A) binding proteins (PABPs) in Arabidopsis is restricted to pollen and ovule development and early embryogenesis [1].
PAB5 and PAB3 RNAs were detected only in floral organs, with the highest level of expression in immature flowers [2].
Poly(A)-binding protein (PABP) is considered an essential component of a eukaryotic cell; deletion of the PABP-coding gene in yeast leads to a lethal phenotype [2].

Analytical, diagnostic and therapeutic context of PAB5

A nested set of degenerate PCR primers designed from regions conserved among yeast, Xenopus, and human PABP sequences was used to amplify genomic DNA fragments from Arabidopsis thaliana [2].

References

A pollen-, ovule-, and early embryo-specific poly(A) binding protein from Arabidopsis complements essential functions in yeast. Belostotsky, D.A., Meagher, R.B. Plant Cell (1996) [Pubmed]
Differential organ-specific expression of three poly(A)-binding-protein genes from Arabidopsis thaliana. Belostotsky, D.A., Meagher, R.B. Proc. Natl. Acad. Sci. U.S.A. (1993) [Pubmed]

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