The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

PHO87  -  Pho87p

Saccharomyces cerevisiae S288c

Synonyms: Inorganic phosphate transporter PHO87, YCR037C, YCR37C, YCR524
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on PHO87

  • Our work further revealed that mutations in the low affinity orthophosphate carrier genes (PHO87, PHO90, and PHO91) cause deregulation of phosphate-repressed genes [1].
  • Pho84 sustained both transport and rapid signalling, whereas Pho87 was poor in transport but positive for signalling [2].
  • The low-affinity system has recently been shown to be composed of Pho87p, Pho90p, and Pho91p [3].
  • Two new genes, PHO86 and PHO87, involved in inorganic phosphate uptake in Saccharomyces cerevisiae [4].

Biological context of PHO87

  • The PHO87 gene was found to be identical with YCR524, according to the published nucleotide sequence of chromosome III, which encodes a protein of 923 amino-acid residues with a highly charged N-terminal half followed by a C-terminal half consisting of 12 membrane-spanning segments as in Pho84p [4].
  • Disruption of PHO86 did not affect cell viability even in combination with the pho84 and/or pho87 disruptions [5].

Associations of PHO87 with chemical compounds

  • These results demonstrate that phosphate acts as a nutrient signal for activation of the protein kinase A pathway in yeast in a glucose-dependent way and they indicate that the Pho84 and Pho87 carriers act as specific phosphate sensors for rapid phosphate signalling [2].


WikiGenes - Universities