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Gene Review

TAF2  -  Taf2p

Saccharomyces cerevisiae S288c

Synonyms: TAF150, TAFII-150, TBP-associated factor 150 kDa, TBP-associated factor 2, TSM-1, ...
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High impact information on TAF2


Associations of TAF2 with chemical compounds

  • Furthermore, we show that in yeast the antagonistic effects of the antiestrogen nafoxidine arise from a modulation of the synergistic interactions of TAF-1 and TAF-2, and not simply from an inactivation of TAF-2 by antihormone [3].


  1. Drosophila TAFII150: similarity to yeast gene TSM-1 and specific binding to core promoter DNA. Verrijzer, C.P., Yokomori, K., Chen, J.L., Tjian, R. Science (1994) [Pubmed]
  2. Systematic analysis of essential yeast TAFs in genome-wide transcription and preinitiation complex assembly. Shen, W.C., Bhaumik, S.R., Causton, H.C., Simon, I., Zhu, X., Jennings, E.G., Wang, T.H., Young, R.A., Green, M.R. EMBO J. (2003) [Pubmed]
  3. Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast. Pham, T.A., Hwung, Y.P., Santiso-Mere, D., McDonnell, D.P., O'Malley, B.W. Mol. Endocrinol. (1992) [Pubmed]
  4. Promoter specificity of the two transcriptional activation functions of the human oestrogen receptor in yeast. Metzger, D., Losson, R., Bornert, J.M., Lemoine, Y., Chambon, P. Nucleic Acids Res. (1992) [Pubmed]
  5. The TSM1 gene of Saccharomyces cerevisiae overlaps the MAT locus. Ray, B.L., White, C.I., Haber, J.E. Curr. Genet. (1991) [Pubmed]
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