Chemical Compound Review:
Nafoxidine 1-[2-[4-(6-methoxy-2-phenyl- 3,4...
Synonyms:
Nafoxidina, Nafoxidinum, CHEMBL28211, SureCN153125, CHEBI:134557, ...
- Estrogens and antiestrogens stimulate release of bone resorbing activity by cultured human breast cancer cells. Valentin-Opran, A., Eilon, G., Saez, S., Mundy, G.R. J. Clin. Invest. (1985)
- Effects of 4-nitroestrone 3-methyl ether on dimethylbenz(a)anthracene-induced mammary tumors. Rozhin, J., Ludwig, E.H., Corombos, J., Odden, D., Horwitz, J.P., Hughes, R., Hughes, D.E., Wilson, E., Brooks, S.C. Cancer Res. (1983)
- Effect of the anti-estrogen, Nafoxidine, on NZB/W autoimmune disease. Duvic, M., Steinberg, A.D., Klassen, L.W. Arthritis Rheum. (1978)
- Gap junction modulation in rat uterus. II. Effects of antiestrogens on myometrial and serosal cells. Burghardt, R.C., Mitchell, P.A., Kurten, R. Biol. Reprod. (1984)
- Dissociation of uterine eosinophilia and water imbibition from other estrogen-induced responses by nafoxidine pretreatment. Galand, P., Tchernitchin, N., Tchernitchin, A.N. Mol. Cell. Endocrinol. (1985)
- Estrogenic properties of 3,9-dihydroxy-7,12-dimethylbenz[a]anthracene in rats. Morreal, C.E., Schneider, S.L., Sinha, D.K., Bronstein, R.E. J. Natl. Cancer Inst. (1979)
- Tumor formation in preneoplastic mammary nodule lines in mice treated with nafoxidine, testosterone, and 2-bromo-alpha-ergocryptine. Medina, D. J. Natl. Cancer Inst. (1977)
- Role of estrogen receptor binding and transcriptional activity in the stimulation of hyperestrogenism and nuclear bodies. Clark, J.H., Hardin, J.W., Padykula, H.A., Cardasis, C.A. Proc. Natl. Acad. Sci. U.S.A. (1978)
- Specific binding and biological response of antiestrogens in the fetal uterus of the guinea pig. Gulino, A., Pasqualini, J.R. Cancer Res. (1980)
- Permanent chondrification in the pelvis and occurrence of hernias in mice treated neonatally with tamoxifen. Iguchi, T., Irisawa, S., Uchima, F.D., Takasugi, N. Reprod. Toxicol. (1988)
- Influence of anti-oestrogens on gonadotrophin secretion in control and ACTH-infused immature rats. Mann, D.R., Blank, M.S., Sridaran, R., Castracane, V.D., Eldridge, C., Collins, D.C. Acta Endocrinol. (1984)
- Controlled clinical trial of L-dopa and nafoxidine in advanced breast cancer: an E.O.R.T.C. study. Engelsman, E., Heuson, J.C., Blonk Van Der Wijst, J., Drochmans, A., Maass, H., Cheix, F., Sobrinho, L.G., Nowakowski, H. British medical journal. (1975)
- Treatment of renal carcinoma: a phase III randomized trial of oral medroxyprogesterone (Provera), hydroxyurea, and nafoxidine. Stolbach, L.L., Begg, C.B., Hall, T., Horton, J. Cancer treatment reports. (1981)
- Effects of anti-estrogens on early pregnancy in guinea pigs. Wisel, M.S., Datta, J.K., Saxena, R.N. International journal of fertility and menopausal studies. (1994)
- Crystal and molecular structure of nafoxidine and stereochemical features of anticancer antiestrogens. Camerman, N., Chan, L.Y., Camerman, A. J. Med. Chem. (1980)
- A high-affinity estrogen-binding protein in rat placental trophoblast. McCormack, S.A., Glasser, S.R. Endocrinology (1976)
- Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen. Horwitz, K.B., Koseki, Y., McGuire, W.L. Endocrinology (1978)
- Antagonism of estrogen receptor and calmodulin association by antiestrogens is not dependent on an interaction with calmodulin. Rowlands, M.G., Grimshaw, R., Jarman, M., Bouhoute, A., Leclercq, G. Biochem. Pharmacol. (1997)
- The antioxidant action of a pure antioestrogen: ability to inhibit lipid peroxidation compared to tamoxifen and 17 beta-oestradiol and relevance to its anticancer potential. Wiseman, H. Biochem. Pharmacol. (1994)
- Effects of estrogen and antiestrogen on DNA polymerase in human breast cancer. Edwards, D.P., Murthy, S.R., McGuire, W.L. Cancer Res. (1980)
- Effect of estrogens on bacterial adherence to HeLa cells. Sugarman, B., Epps, L.R. Infect. Immun. (1982)
- Stimulatory and inhibitory effects of estrogen and antiestrogen on uterine cell division. Mukku, V.R., Kirkland, J.L., Hardy, M., Stancel, G.M. Endocrinology (1981)
- Effects of tamoxifen, tamoxifen metabolites, and nafoxidine on adenosine 3',5'-monophosphate phosphodiesterase: correlations with growth inhibitory activities but not estrogen receptor affinities. Fanidi, A., Courion-Guichardaz, C., Fayard, J.M., Pageaux, J.F., Laugier, C. Endocrinology (1989)
- Estrogen stimulation of 3-o-methyl-D-glucose uptake in isolated rat hepatocytes. Madar, Z., MacLusky, N.J., Naftolin, F. Endocrinology (1982)
- Female steroid hormones and lipoprotein synthesis in the cockerel: effects of progesterone and nafoxidine on the estrogenic stimulation of very low density lipoproteins (VLDL) synthesis. Chan, L., Jackson, R.L., Means, A.R. Endocrinology (1977)
- Effects of nafoxidine on the luteinizing hormone surge: temporal distribution of estrogen receptors and induction of cytoplasmic progestin receptors in the hypothalamus-preoptic area, pituitary, and uterus of the immature rat. Attardi, B., Palumbo, L.A. Endocrinology (1981)
- Inhibition of volume-regulated anion channels in cultured endothelial cells by the anti-oestrogens clomiphene and nafoxidine. Maertens, C., Droogmans, G., Chakraborty, P., Nilius, B. Br. J. Pharmacol. (2001)
- Effect of neonatal exposure to the antioestrogens nafoxidine and CI-628 upon the development of the uterus in the prepubertal rat. Campbell, P.S., Satterfield, P.M. J. Reprod. Fertil. (1988)
- Changes in the uterus and vagina of mice treated neonatally with antiestrogens. Iguchi, T., Todoroki, R., Yamaguchi, S., Takasugi, N. Acta anatomica. (1989)
- Antiestrogens inhibit endothelial cell growth stimulated by angiogenic growth factors. Gagliardi, A.R., Hennig, B., Collins, D.C. Anticancer Res. (1996)
- Nafoxidine modulates the expression of matrix-metalloproteinase-2 (MMP-2) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in endothelial cells. De Lorenzo, M.S., Alonso, D.F., Gomez, D.E. Anticancer Res. (2000)
- Ligand-dependent and -independent function of the transactivation regions of the human estrogen receptor in yeast. Pham, T.A., Hwung, Y.P., Santiso-Mere, D., McDonnell, D.P., O'Malley, B.W. Mol. Endocrinol. (1992)
- Modulation of the estradiol-induced luteinizing hormone surge by progesterone or antiestrogens: effects on pituitary gonadotropin-releasing hormone receptors. Attardi, B., Happe, H.K. Endocrinology (1986)
- Selective blockade of estrogen-induced uterine responses by the antiestrogen nafoxidine. Gardner, R.M., Kirkland, J.L., Stancel, G.M. Endocrinology (1978)
- Clinical trial of nafoxidine in adrenalectomized patients with advanced breast cancer. Jain, J., Samal, B., Singhakowinta, A., Vaitkevicius, V.K. Cancer (1977)