Gene Review:
VCX1 - Vcx1p
Saccharomyces cerevisiae S288c
Synonyms:
HUM1, High copy number undoes manganese protein 1, MNR1, Manganese resistance 1 protein, Vacuolar Ca(2+)/H(+) exchanger, ...
- Internal Ca(2+) release in yeast is triggered by hypertonic shock and mediated by a TRP channel homologue. Denis, V., Cyert, M.S. J. Cell Biol. (2002)
- The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Pozos, T.C., Sekler, I., Cyert, M.S. Mol. Cell. Biol. (1996)
- Functional dependence on calcineurin by variants of the Saccharomyces cerevisiae vacuolar Ca2+/H+ exchanger Vcx1p. Pittman, J.K., Cheng, N.H., Shigaki, T., Kunta, M., Hirschi, K.D. Mol. Microbiol. (2004)
- A single nucleotide change in the MNR1 (VCX1/HUM1) gene determines resistance to manganese in Saccharomyces cerevisiae. del Pozo, L., Osaba, L., Corchero, J., Jimenez, A. Yeast (1999)
- Manganese toxicity and Saccharomyces cerevisiae Mam3p, a member of the ACDP (ancient conserved domain protein) family. Yang, M., Jensen, L.T., Gardner, A.J., Culotta, V.C. Biochem. J. (2005)