Gene Review:
VPH1 - H(+)-transporting V0 sector ATPase subunit a
Saccharomyces cerevisiae S288c
Synonyms:
V-ATPase 95 kDa subunit, V-ATPase a 1 subunit, V-type proton ATPase subunit a, vacuolar isoform, Vacuolar pH protein 1, Vacuolar proton pump a subunit, ...
- Action of BTN1, the yeast orthologue of the gene mutated in Batten disease. Pearce, D.A., Ferea, T., Nosel, S.A., Das, B., Sherman, F. Nat. Genet. (1999)
- Degradation of unassembled Vph1p reveals novel aspects of the yeast ER quality control system. Hill, K., Cooper, A.A. EMBO J. (2000)
- The membrane protein alkaline phosphatase is delivered to the vacuole by a route that is distinct from the VPS-dependent pathway. Piper, R.C., Bryant, N.J., Stevens, T.H. J. Cell Biol. (1997)
- Elicitor-activated phospholipase A(2) generates lysophosphatidylcholines that mobilize the vacuolar H(+) pool for pH signaling via the activation of Na(+)-dependent proton fluxes. Viehweger, K., Dordschbal, B., Roos, W. Plant Cell (2002)
- Arg-735 of the 100-kDa subunit a of the yeast V-ATPase is essential for proton translocation. Kawasaki-Nishi, S., Nishi, T., Forgac, M. Proc. Natl. Acad. Sci. U.S.A. (2001)
- Characterization of yeast V-ATPase mutants lacking Vph1p or Stv1p and the effect on endocytosis. Perzov, N., Padler-Karavani, V., Nelson, H., Nelson, N. J. Exp. Biol. (2002)
- Evidence for a conserved 95-120 kDa subunit associated with and essential for activity of V-ATPases. Manolson, M.F., Proteau, D., Jones, E.W. J. Exp. Biol. (1992)
- DNA sequence analysis of the VPH1-SNF2 region on chromosome XV of Saccharomyces cerevisiae. Chéret, G., Bernardi, A., Sor, F. Yeast (1996)
- Yeast V-ATPase complexes containing different isoforms of the 100-kDa a-subunit differ in coupling efficiency and in vivo dissociation. Kawasaki-Nishi, S., Nishi, T., Forgac, M. J. Biol. Chem. (2001)
- Assay of vacuolar pH in yeast and identification of acidification-defective mutants. Preston, R.A., Murphy, R.F., Jones, E.W. Proc. Natl. Acad. Sci. U.S.A. (1989)
- STV1 gene encodes functional homologue of 95-kDa yeast vacuolar H(+)-ATPase subunit Vph1p. Manolson, M.F., Wu, B., Proteau, D., Taillon, B.E., Roberts, B.T., Hoyt, M.A., Jones, E.W. J. Biol. Chem. (1994)
- PKR1 Encodes an Assembly Factor for the Yeast V-Type ATPase. Davis-Kaplan, S.R., Compton, M.A., Flannery, A.R., Ward, D.M., Kaplan, J., Stevens, T.H., Graham, L.A. J. Biol. Chem. (2006)
- Phenotypic reversal of the btn1 defects in yeast by chloroquine: a yeast model for Batten disease. Pearce, D.A., Carr, C.J., Das, B., Sherman, F. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Evidence that the NH2 terminus of vph1p, an integral subunit of the V0 sector of the yeast V-ATPase, interacts directly with the Vma1p and Vma13p subunits of the V1 sector. Landolt-Marticorena, C., Williams, K.M., Correa, J., Chen, W., Manolson, M.F. J. Biol. Chem. (2000)
- Transmembrane topography of the 100-kDa a subunit (Vph1p) of the yeast vacuolar proton-translocating ATPase. Leng, X.H., Nishi, T., Forgac, M. J. Biol. Chem. (1999)
- Assembly of the yeast vacuolar H+-ATPase occurs in the endoplasmic reticulum and requires a Vma12p/Vma22p assembly complex. Graham, L.A., Hill, K.J., Stevens, T.H. J. Cell Biol. (1998)
- Role of Vma21p in assembly and transport of the yeast vacuolar ATPase. Malkus, P., Graham, L.A., Stevens, T.H., Schekman, R. Mol. Biol. Cell (2004)
- The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Pozos, T.C., Sekler, I., Cyert, M.S. Mol. Cell. Biol. (1996)
- Vma9p (subunit e) is an integral membrane V0 subunit of the yeast V-ATPase. Compton, M.A., Graham, L.A., Stevens, T.H. J. Biol. Chem. (2006)
- Site-directed mutagenesis of the 100-kDa subunit (Vph1p) of the yeast vacuolar (H+)-ATPase. Leng, X.H., Manolson, M.F., Liu, Q., Forgac, M. J. Biol. Chem. (1996)
- The VPH1 gene encodes a 95-kDa integral membrane polypeptide required for in vivo assembly and activity of the yeast vacuolar H(+)-ATPase. Manolson, M.F., Proteau, D., Preston, R.A., Stenbit, A., Roberts, B.T., Hoyt, M.A., Preuss, D., Mulholland, J., Botstein, D., Jones, E.W. J. Biol. Chem. (1992)
- Visualization of receptor-mediated endocytosis in yeast. Mulholland, J., Konopka, J., Singer-Kruger, B., Zerial, M., Botstein, D. Mol. Biol. Cell (1999)