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Gene Review

LIP5  -  putative lipoate synthase

Saccharomyces cerevisiae S288c

Synonyms: LS, Lip-syn, Lipoate synthase, Lipoic acid synthase, Lipoyl synthase, mitochondrial, ...
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Disease relevance of LIP5

  • Relative to the E. coli lip gene product, the LIP5 protein has an amino-terminal extension with characteristics of mitochondrial targeting signals [1].

High impact information on LIP5


Biological context of LIP5

  • The results presented indicate that the Kgd1 and Lip5 proteins are important for the expression of genes encoding peroxisomal matrix proteins, although they are not necessary for the biogenesis of this cellular compartment [2].


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