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Gene Review

WSC2  -  Wsc2p

Saccharomyces cerevisiae S288c

Synonyms: Cell wall integrity and stress response component 2, N0583, YNL283C
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Disease relevance of WSC2


High impact information on WSC2

  • Overexpression of WSC2 reverses the heat-induced cell cycle arrest of rad6-149 but not of rad6 null mutants [2].
  • Deletion of WSC1 causes a cell lysis defect that is exacerbated by deleting WSC2 or WSC3 [3].
  • In a genetic screening for multicopy suppressors of the rsp5 mutation, we identified the WSC2/YNL283c gene [4].
  • Deletion of the WSC2 gene disturbs ATPase activation by glucose, abolishing the K(m) decrease that occurs during this process [4].
  • Wsc2 is a component of the PKC1-MPK1 mitogen-activated protein kinase (MAPK) signaling pathway that controls the cell wall integrity [4].

Anatomical context of WSC2


Other interactions of WSC2


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