Gene Review:
PKC1 - protein kinase C
Saccharomyces cerevisiae S288c
Synonyms:
CLY15, CLY5, CLY7, HPO2, PKC 1, ...
Levin,
Herskowitz,
Leiper,
Trópia,
Gray,
Stark,
Castro,
Thevelein,
Stone,
Carling,
Queiroz,
Gonçalves,
Yuqi Wang,
Ming Zhu,
Mihretu Ayalew,
Jack A. Ruff,
Andrews,
Guiet,
Kamada,
D'Adamio,
Ogas,
Ernandes,
Vito,
Winderickx,
Loureiro-Dias,
Pellegrini,
Brandão,
Etchebehere,
- Saccharomyces cerevisiae YCRO17c/CWH43 encodes a putative sensor/transporter protein upstream of the BCK2 branch of the PKC1-dependent cell wall integrity pathway. Martin-Yken, H., Dagkessamanskaia, A., De Groot, P., Ram, A., Klis, F., François, J. Yeast (2001)
- Activation of the protein kinase C1 pathway upon continuous heat stress in Saccharomyces cerevisiae is triggered by an intracellular increase in osmolarity due to trehalose accumulation. Mensonides, F.I., Brul, S., Klis, F.M., Hellingwerf, K.J., Teixeira de Mattos, M.J. Appl. Environ. Microbiol. (2005)
- Saccharomyces cerevisiae PKC1 encodes a protein kinase C (PKC) homolog with a substrate specificity similar to that of mammalian PKC. Watanabe, M., Chen, C.Y., Levin, D.E. J. Biol. Chem. (1994)
- Protein kinase C in yeast. Characteristics of the Saccharomyces cerevisiae PKC1 gene product. Antonsson, B., Montessuit, S., Friedli, L., Payton, M.A., Paravicini, G. J. Biol. Chem. (1994)
- Purification of two Bacillus subtilis proteins which cross-react with antibodies directed against eukaryotic protein kinase C, the His HPr kinase and trigger factor. Zouari, N., Roche, B., Seegers, J.F., Séror, S. Microbiology (Reading, Engl.) (1997)
- A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle. Levin, D.E., Fields, F.O., Kunisawa, R., Bishop, J.M., Thorner, J. Cell (1990)
- Rho1p, a yeast protein at the interface between cell polarization and morphogenesis. Drgonová, J., Drgon, T., Tanaka, K., Kollár, R., Chen, G.C., Ford, R.A., Chan, C.S., Takai, Y., Cabib, E. Science (1996)
- The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response. Kamada, Y., Jung, U.S., Piotrowski, J., Levin, D.E. Genes Dev. (1995)
- Mutations in WSC genes for putative stress receptors result in sensitivity to multiple stress conditions and impairment of Rlm1-dependent gene expression in Saccharomyces cerevisiae. Zu, T., Verna, J., Ballester, R. Mol. Genet. Genomics (2001)
- Aberrant processing of the WSC family and Mid2p cell surface sensors results in cell death of Saccharomyces cerevisiae O-mannosylation mutants. Lommel, M., Bagnat, M., Strahl, S. Mol. Cell. Biol. (2004)
- A pair of functionally redundant yeast genes (PPZ1 and PPZ2) encoding type 1-related protein phosphatases function within the PKC1-mediated pathway. Lee, K.S., Hines, L.K., Levin, D.E. Mol. Cell. Biol. (1993)
- Functional interaction between the PKC1 pathway and CDC31 network of SPB duplication genes. Khalfan, W., Ivanovska, I., Rose, M.D. Genetics (2000)
- Yeast RSC function is required for organization of the cellular cytoskeleton via an alternative PKC1 pathway. Chai, B., Hsu, J.M., Du, J., Laurent, B.C. Genetics (2002)
- PKC1, a protein kinase C homologue of Saccharomyces cerevisiae, participates in microtubule function through the yeast EB1 homologue, BIM1. Hosotani, T., Koyama, H., Uchino, M., Miyakawa, T., Tsuchiya, E. Genes Cells (2001)
- Regulation of organelle membrane fusion by Pkc1p. Lin, A., Patel, S., Latterich, M. Traffic (2001)
- The interaction of Slt2 MAP kinase with Knr4 is necessary for signalling through the cell wall integrity pathway in Saccharomyces cerevisiae. Martin-Yken, H., Dagkessamanskaia, A., Basmaji, F., Lagorce, A., Francois, J. Mol. Microbiol. (2003)
- Suppressor analysis of the mpt5/htr1/uth4/puf5 deletion in Saccharomyces cerevisiae. Ohkuni, K., Kikuchi, Y., Hara, K., Taneda, T., Hayashi, N., Kikuchi, A. Mol. Genet. Genomics (2006)
- Characterization of the yeast (1-->6)-beta-glucan biosynthetic components, Kre6p and Skn1p, and genetic interactions between the PKC1 pathway and extracellular matrix assembly. Roemer, T., Paravicini, G., Payton, M.A., Bussey, H. J. Cell Biol. (1994)
- Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin. Lesage, G., Sdicu, A.M., Ménard, P., Shapiro, J., Hussein, S., Bussey, H. Genetics (2004)
- A novel role for the mating type (MAT) locus in the maintenance of cell wall integrity in Saccharomyces cerevisiae. Verna, J., Ballester, R. Mol. Gen. Genet. (1999)
- A downstream target of RHO1 small GTP-binding protein is PKC1, a homolog of protein kinase C, which leads to activation of the MAP kinase cascade in Saccharomyces cerevisiae. Nonaka, H., Tanaka, K., Hirano, H., Fujiwara, T., Kohno, H., Umikawa, M., Mino, A., Takai, Y. EMBO J. (1995)
- KNR4 is a member of the PKC1 signalling pathway and genetically interacts with BCK2, a gene involved in cell cycle progression in Saccharomyces cerevisiae. Martin-Yken, H., Dagkessamanskaia, A., Talibi, D., Francois, J. Curr. Genet. (2002)
- Sphingoid base signaling via Pkh kinases is required for endocytosis in yeast. Friant, S., Lombardi, R., Schmelzle, T., Hall, M.N., Riezman, H. EMBO J. (2001)
- Regulation of yeast CTP synthetase activity by protein kinase C. Yang, W.L., Bruno, M.E., Carman, G.M. J. Biol. Chem. (1996)
- A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator. Gray, J.V., Ogas, J.P., Kamada, Y., Stone, M., Levin, D.E., Herskowitz, I. EMBO J. (1997)
- Evidence for involvement of Saccharomyces cerevisiae protein kinase C in glucose induction of HXT genes and derepression of SUC2. Brandão, R.L., Etchebehere, L., Queiroz, C.C., Trópia, M.J., Ernandes, J.R., Gonçalves, T., Loureiro-Dias, M.C., Winderickx, J., Thevelein, J.M., Leiper, F.C., Carling, D., Castro, I.M. FEMS Yeast Res. (2002)
- A role for Sds3p, a component of the Rpd3p/Sin3p deacetylase complex, in maintaining cellular integrity in Saccharomyces cerevisiae. Vannier, D., Damay, P., Shore, D. Mol. Genet. Genomics (2001)
- The hypo-osmolarity-sensitive phenotype of the Saccharomyces cerevisiae hpo2 mutant is due to a mutation in PKC1, which regulates expression of beta-glucanase. Shimizu, J., Yoda, K., Yamasaki, M. Mol. Gen. Genet. (1994)
- Down-regulation of Pkc1-mediated signaling by the deubiquitinating enzyme Ubp3. Wang, Y., Zhu, M., Ayalew, M., Ruff, J.A. J. Biol. Chem. (2008)
- The osmotic integrity of the yeast cell requires a functional PKC1 gene product. Paravicini, G., Cooper, M., Friedli, L., Smith, D.J., Carpentier, J.L., Klig, L.S., Payton, M.A. Mol. Cell. Biol. (1992)
- Cloning of AIP1, a novel protein that associates with the apoptosis-linked gene ALG-2 in a Ca2+-dependent reaction. Vito, P., Pellegrini, L., Guiet, C., D'Adamio, L. J. Biol. Chem. (1999)
- Dynamic, Rho1p-dependent localization of Pkc1p to sites of polarized growth. Andrews, P.D., Stark, M.J. J. Cell. Sci. (2000)
- Characterization of a protein kinase C gene in Sporothrix schenckii and its expression during the yeast-to-mycelium transition. Aquino-Piñero, E., Rodríguez-del Valle, N. Med. Mycol. (2002)