Gene Review:
SLT2 - mitogen-activated serine/threonine-protein...
Saccharomyces cerevisiae S288c
Synonyms:
BYC2, LYT2, MAP kinase MPK1, MPK1, Mitogen-activated protein kinase SLT2/MPK1, ...
- A novel connection between the yeast Cdc42 GTPase and the Slt2-mediated cell integrity pathway identified through the effect of secreted Salmonella GTPase modulators. Rodríguez-Pachón, J.M., Martín, H., North, G., Rotger, R., Nombela, C., Molina, M. J. Biol. Chem. (2002)
- The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function. Kraus, P.R., Fox, D.S., Cox, G.M., Heitman, J. Mol. Microbiol. (2003)
- Regulation of the oxidative stress response through Slt2p-dependent destruction of cyclin C in Saccharomyces cerevisiae. Krasley, E., Cooper, K.F., Mallory, M.J., Dunbrack, R., Strich, R. Genetics (2006)
- Sir3p phosphorylation by the Slt2p pathway effects redistribution of silencing function and shortened lifespan. Ray, A., Hector, R.E., Roy, N., Song, J.H., Berkner, K.L., Runge, K.W. Nat. Genet. (2003)
- Role of calcineurin and Mpk1 in regulating the onset of mitosis in budding yeast. Mizunuma, M., Hirata, D., Miyahara, K., Tsuchiya, E., Miyakawa, T. Nature (1998)
- The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response. Kamada, Y., Jung, U.S., Piotrowski, J., Levin, D.E. Genes Dev. (1995)
- The SLT2 (MPK1) MAP kinase homolog is involved in polarized cell growth in Saccharomyces cerevisiae. Mazzoni, C., Zarov, P., Rambourg, A., Mann, C. J. Cell Biol. (1993)
- A role for the Pkc1 MAP kinase pathway of Saccharomyces cerevisiae in bud emergence and identification of a putative upstream regulator. Gray, J.V., Ogas, J.P., Kamada, Y., Stone, M., Levin, D.E., Herskowitz, I. EMBO J. (1997)
- A yeast mitogen-activated protein kinase homolog (Mpk1p) mediates signalling by protein kinase C. Lee, K.S., Irie, K., Gotoh, Y., Watanabe, Y., Araki, H., Nishida, E., Matsumoto, K., Levin, D.E. Mol. Cell. Biol. (1993)
- Yeast RLM1 encodes a serum response factor-like protein that may function downstream of the Mpk1 (Slt2) mitogen-activated protein kinase pathway. Watanabe, Y., Irie, K., Matsumoto, K. Mol. Cell. Biol. (1995)
- Transcriptional coregulation by the cell integrity mitogen-activated protein kinase Slt2 and the cell cycle regulator Swi4. Baetz, K., Moffat, J., Haynes, J., Chang, M., Andrews, B. Mol. Cell. Biol. (2001)
- Role for lipid signaling and the cell integrity MAP kinase cascade in yeast septum biogenesis. Tahirovic, S., Schorr, M., Then, A., Berger, J., Schwarz, H., Mayinger, P. Curr. Genet. (2003)
- Spa2p functions as a scaffold-like protein to recruit the Mpk1p MAP kinase module to sites of polarized growth. van Drogen, F., Peter, M. Curr. Biol. (2002)
- Cell wall perturbation in yeast results in dual phosphorylation of the Slt2/Mpk1 MAP kinase and in an Slt2-mediated increase in FKS2-lacZ expression, glucanase resistance and thermotolerance. de Nobel, H., Ruiz, C., Martin, H., Morris, W., Brul, S., Molina, M., Klis, F.M. Microbiology (Reading, Engl.) (2000)
- The cell wall integrity/remodeling MAPK cascade is involved in glucose activation of the yeast plasma membrane H(+)-ATPase. de la Fuente, N., Portillo, F. Biochim. Biophys. Acta (2000)
- Characterization of domains in the yeast MAP kinase Slt2 (Mpk1) required for functional activity and in vivo interaction with protein kinases Mkk1 and Mkk2. Soler, M., Plovins, A., Martín, H., Molina, M., Nombela, C. Mol. Microbiol. (1995)
- A synthetic lethal screen identifies a role for the cortical actin patch/endocytosis complex in the response to nutrient deprivation in Saccharomyces cerevisiae. Care, A., Vousden, K.A., Binley, K.M., Radcliffe, P., Trevethick, J., Mannazzu, I., Sudbery, P.E. Genetics (2004)
- Saccharomyces cerevisiae mid2p is a potential cell wall stress sensor and upstream activator of the PKC1-MPK1 cell integrity pathway. Ketela, T., Green, R., Bussey, H. J. Bacteriol. (1999)
- The interaction of Slt2 MAP kinase with Knr4 is necessary for signalling through the cell wall integrity pathway in Saccharomyces cerevisiae. Martin-Yken, H., Dagkessamanskaia, A., Basmaji, F., Lagorce, A., Francois, J. Mol. Microbiol. (2003)
- Reciprocal regulation between Slt2 MAPK and isoforms of Msg5 dual-specificity protein phosphatase modulates the yeast cell integrity pathway. Flández, M., Cosano, I.C., Nombela, C., Martín, H., Molina, M. J. Biol. Chem. (2004)
- Differential regulation of the cell wall integrity mitogen-activated protein kinase pathway in budding yeast by the protein tyrosine phosphatases Ptp2 and Ptp3. Mattison, C.P., Spencer, S.S., Kresge, K.A., Lee, J., Ota, I.M. Mol. Cell. Biol. (1999)
- Regulation of the yeast Rlm1 transcription factor by the Mpk1 cell wall integrity MAP kinase. Jung, U.S., Sobering, A.K., Romeo, M.J., Levin, D.E. Mol. Microbiol. (2002)
- Genetic evidence for the functional redundancy of the calcineurin- and Mpk1-mediated pathways in the regulation of cellular events important for growth in Saccharomyces cerevisiae. Nakamura, T., Ohmoto, T., Hirata, D., Tsuchiya, E., Miyakawa, T. Mol. Gen. Genet. (1996)
- The Rho1 effector Pkc1, but not Bni1, mediates signalling from Tor2 to the actin cytoskeleton. Helliwell, S.B., Schmidt, A., Ohya, Y., Hall, M.N. Curr. Biol. (1998)
- Response of the Saccharomyces cerevisiae Mpk1 mitogen-activated protein kinase pathway to increases in internal turgor pressure caused by loss of Ppz protein phosphatases. Merchan, S., Bernal, D., Serrano, R., Yenush, L. Eukaryotic Cell (2004)
- GSK-3 kinase Mck1 and calcineurin coordinately mediate Hsl1 down-regulation by Ca2+ in budding yeast. Mizunuma, M., Hirata, D., Miyaoka, R., Miyakawa, T. EMBO J. (2001)
- Molecular and functional characterization of a mutant allele of the mitogen-activated protein-kinase gene SLT2(MPK1) rescued from yeast autolytic mutants. Martín, H., Castellanos, M.C., Cenamor, R., Sánchez, M., Molina, M., Nombela, C. Curr. Genet. (1996)
- Oxidative stress activates FUS1 and RLM1 transcription in the yeast Saccharomyces cerevisiae in an oxidant-dependent Manner. Staleva, L., Hall, A., Orlow, S.J. Mol. Biol. Cell (2004)
- Protein-protein interactions in the yeast PKC1 pathway: Pkc1p interacts with a component of the MAP kinase cascade. Paravicini, G., Friedli, L. Mol. Gen. Genet. (1996)
- Activity of the yeast MAP kinase homologue Slt2 is critically required for cell integrity at 37 degrees C. Martín, H., Arroyo, J., Sánchez, M., Molina, M., Nombela, C. Mol. Gen. Genet. (1993)