The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

PA3435  -  flavodoxin

Pseudomonas aeruginosa PAO1

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of PA3435

  • The results demonstrate that the apparent interaction site charge with flavodoxin is larger than that with FMN for plastocyanin, nitrite reductase, and stellacyanin but smaller for Pseudomonas azurin [1].

High impact information on PA3435

  • Transient kinetics of reduction of blue copper proteins by free flavin and flavodoxin semiquinones [1].
  • Interestingly, each WrbA protein forms a homotetramer with 222 symmetry, unique among flavodoxin-like proteins, in which each protomer binds one flavin mononucleotide cofactor molecule [2].
  • Although this protein lacks the flavodoxin key fingerprint motif [(T/S)XTGXT], it has been confirmed to bind flavin mononucleotide and the binding site was identified via X-ray crystallography [3].

Associations of PA3435 with chemical compounds

  • The intrinsic reactivities of plastocyanin and azurin toward flavodoxin are the same, as was the case with FMN, but both stellacyanin and nitrite reductase are considerably less reactive than expected (approximately 2 orders of magnitude) [1].


  1. Transient kinetics of reduction of blue copper proteins by free flavin and flavodoxin semiquinones. Tollin, G., Meyer, T.E., Cheddar, G., Getzoff, E.D., Cusanovich, M.A. Biochemistry (1986) [Pubmed]
  2. Crystal structures of the tryptophan repressor binding protein WrbA and complexes with flavin mononucleotide. Gorman, J., Shapiro, L. Protein Sci. (2005) [Pubmed]
  3. Structure determination of an FMN reductase from Pseudomonas aeruginosa PA01 using sulfur anomalous signal. Agarwal, R., Bonanno, J.B., Burley, S.K., Swaminathan, S. Acta Crystallogr. D Biol. Crystallogr. (2006) [Pubmed]
WikiGenes - Universities