Gene Review:
gacA - response regulator GacA
Pseudomonas aeruginosa PAO1
- The global activator GacA of Pseudomonas aeruginosa PAO positively controls the production of the autoinducer N-butyryl-homoserine lactone and the formation of the virulence factors pyocyanin, cyanide, and lipase. Reimmann, C., Beyeler, M., Latifi, A., Winteler, H., Foglino, M., Lazdunski, A., Haas, D. Mol. Microbiol. (1997)
- Common virulence factors for bacterial pathogenicity in plants and animals. Rahme, L.G., Stevens, E.J., Wolfort, S.F., Shao, J., Tompkins, R.G., Ausubel, F.M. Science (1995)
- Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors. Tan, M.W., Rahme, L.G., Sternberg, J.A., Tompkins, R.G., Ausubel, F.M. Proc. Natl. Acad. Sci. U.S.A. (1999)
- Two GacA-dependent small RNAs modulate the quorum-sensing response in Pseudomonas aeruginosa. Kay, E., Humair, B., Dénervaud, V., Riedel, K., Spahr, S., Eberl, L., Valverde, C., Haas, D. J. Bacteriol. (2006)
- Pathogenicity of gacA mutant of Pseudomonas aeruginosa PA01 in the silkworm, Bombyx mori. Chieda, Y., Iiyama, K., Yasunaga-Aoki, C., Lee, J.M., Kusakabe, T., Shimizu, S. FEMS Microbiol. Lett. (2005)
- Pseudomonas aeruginosa GacA, a factor in multihost virulence, is also essential for biofilm formation. Parkins, M.D., Ceri, H., Storey, D.G. Mol. Microbiol. (2001)